Andrographolide promotes hippocampal neurogenesis and spatial memory in the APPswe/PS1ΔE9 mouse model of Alzheimer’s disease

QR Code

Andrographolide promotes hippocampal neurogenesis and spatial memory in the APPswe/PS1ΔE9 mouse model of Alzheimer’s disease

Abstract In Alzheimer´s disease (AD) there is a reduction in hippocampal neurogenesis that has been associated to cognitive deficits. Previously we showed that Andrographolide (ANDRO), the main bioactive component of Andrographis paniculate, induces proliferation in the hippocampus of the APPswe/PSE...

Description complète

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Sebastian B. Arredondo, Daniel T. Reyes, Andrea Herrera-Soto, Muriel D. Mardones, Nibaldo C. Inestrosa, Lorena Varela-Nallar
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2021
Sujets:	Medicine R Science Q
Accès en ligne:	https://doaj.org/article/ca4b966c21c9405888f78dead9baf1c9
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires

A novel retro-inverso peptide inhibitor reduces amyloid deposition, oxidation and inflammation and stimulates neurogenesis in the APPswe/PS1ΔE9 mouse model of Alzheimer's disease.
par: Vadivel Parthsarathy, et autres
Publié: (2013)

Genome-wide analysis of miRNA signature in the APPswe/PS1ΔE9 mouse model of alzheimer's disease.
par: Hongxue Luo, et autres
Publié: (2014)

Deficit in hippocampal ripples does not preclude spatial memory formation in APP/PS1 mice
par: Bartosz Jura, et autres
Publié: (2019)

Early β adrenoceptor dependent time window for fear memory persistence in APPswe/PS1dE9 mice
par: Smitha Karunakaran
Publié: (2021)

Wnt5a promotes hippocampal postsynaptic development and GluN2B-induced expression via the eIF2α HRI kinase
par: Eva Ramos-Fernández, et autres
Publié: (2021)

Impairments of spatial memory in an Alzheimer’s disease model via degeneration of hippocampal cholinergic synapses
par: Houze Zhu, et autres
Publié: (2017)

nAChRs gene expression and neuroinflammation in APPswe/PS1dE9 transgenic mouse
par: D’Angelo Chiara, et autres
Publié: (2021)

Cattle encephalon glycoside and ignotin injection improves cognitive impairment in APPswe/PS1dE9 mice used as multitarget anti-Alzheimer’s drug candidates
par: Gao Y, et autres
Publié: (2015)

Intermittent hypoxia treatment alleviates memory impairment in the 6-month-old APPswe/PS1dE9 mice and reduces amyloid beta accumulation and inflammation in the brain
par: Xiangpei Yue, et autres
Publié: (2021)

Publisher Correction: nAChRs gene expression and neuroinflammation in APPswe/PS1dE9 transgenic mouse
par: Chiara D’Angelo, et autres
Publié: (2021)

IGF2 ameliorates amyloidosis, increases cholinergic marker expression and raises BMP9 and neurotrophin levels in the hippocampus of the APPswePS1dE9 Alzheimer's disease model mice.
par: Tiffany J Mellott, et autres
Publié: (2014)

Effect of metformin treatment on memory and hippocampal neurogenesis decline correlated with oxidative stress induced by methotrexate in rats
par: Nataya Sritawan, et autres
Publié: (2021)

The role of additive neurogenesis and synaptic plasticity in a hippocampal memory model with grid-cell like input.
par: Peter A Appleby, et autres
Publié: (2011)

Increasing neurogenesis refines hippocampal activity rejuvenating navigational learning strategies and contextual memory throughout life
par: Gabriel Berdugo-Vega, et autres
Publié: (2020)

Contribution of cerebellar sensorimotor adaptation to hippocampal spatial memory.
par: Jean-Baptiste Passot, et autres
Publié: (2012)

On null spatial Ps and their arguments
par: Ahonto Terzi
Publié: (2010)

Wnt-5a-regulated miR-101b controls COX2 expression in hippocampal neurons
par: Codocedo,Juan Francisco, et autres
Publié: (2016)

Author Correction: Increasing neurogenesis refines hippocampal activity rejuvenating navigational learning strategies and contextual memory throughout life
par: Gabriel Berdugo-Vega, et autres
Publié: (2020)

Huperzine A and Its Neuroprotective Molecular Signaling in Alzheimer’s Disease
par: María Jesús Friedli, et autres
Publié: (2021)

Milrinone Ameliorates the Neuroinflammation and Memory Function of Alzheimer’s Disease in an APP/PS1 Mouse Model
par: Chen Q, et autres
Publié: (2021)

The functional links between prion protein and copper
par: VARELA-NALLAR,LORENA, et autres
Publié: (2006)

Stage-dependent effects of intermittent hypoxia influence the outcome of hippocampal adult neurogenesis
par: Maggie A. Khuu, et autres
Publié: (2021)

Lateralized hippocampal oscillations underlie distinct aspects of human spatial memory and navigation
par: Jonathan Miller, et autres
Publié: (2018)

The lateralization of left hippocampal CA3 during the retrieval of spatial working memory
par: Da Song, et autres
Publié: (2020)

The mammalian adult neurogenesis gene ontology (MANGO) provides a structural framework for published information on genes regulating adult hippocampal neurogenesis.
par: Rupert W Overall, et autres
Publié: (2012)

Deficits in N-Methyl-D-Aspartate Receptor Function and Synaptic Plasticity in Hippocampal CA1 in APP/PS1 Mouse Model of Alzheimer’s Disease
par: Le Xu, et autres
Publié: (2021)

On cognitive ecology and the environmental factors that promote Alzheimer disease: lessons from Octodon degus (Rodentia: Octodontidae)
par: Rivera,Daniela S., et autres
Publié: (2016)

Engineered andrographolide nanosystems for smart recovery in hepatotoxic conditions
par: Roy P, et autres
Publié: (2014)

Long-term exposure to a hypomagnetic field attenuates adult hippocampal neurogenesis and cognition
par: Bingfang Zhang, et autres
Publié: (2021)

Exercise-induced increases of corticosterone contribute to exercise-enhanced adult hippocampal neurogenesis in mice
par: Tzu-Feng Wang, et autres
Publié: (2021)

Deletion of running-induced hippocampal neurogenesis by irradiation prevents development of an anxious phenotype in mice.
par: Johannes Fuss, et autres
Publié: (2010)

Delayed and transient increase of adult hippocampal neurogenesis by physical exercise in DBA/2 mice.
par: Rupert W Overall, et autres
Publié: (2013)

Gamma Radiation-induced Impairment of Hippocampal Neurogenesis,Comparison of Single and Fractionated Dose Regimens
par: Khoshbin khoshnazar,A. R, et autres
Publié: (2012)

Fetal growth restriction impairs hippocampal neurogenesis and cognition via Tet1 in offspring
par: Wen Chen, et autres
Publié: (2021)

Biodegradable andrographolide-eluting nanofibrous membranes for the treatment of cervical cancer
par: Chen YP, et autres
Publié: (2019)

Gender-Related Differences in BMP Expression and Adult Hippocampal Neurogenesis within Joint-Hippocampal Axis in a Rat Model of Rheumatoid Arthritis
par: Hrvoje Omrčen, et autres
Publié: (2021)

Effects of enriched physical and social environments on motor performance, associative learning, and hippocampal neurogenesis in mice.
par: Noelia Madroñal, et autres
Publié: (2010)

Oxytocin stimulates hippocampal neurogenesis via oxytocin receptor expressed in CA3 pyramidal neurons
par: Yu-Ting Lin, et autres
Publié: (2017)

Subchronic peripheral neuregulin-1 increases ventral hippocampal neurogenesis and induces antidepressant-like effects.
par: Ian Mahar, et autres
Publié: (2011)

EAAC1 gene deletion reduces adult hippocampal neurogenesis after transient cerebral ischemia
par: Bo Young Choi, et autres
Publié: (2018)