Phosphatidylethanolamine made in the inner mitochondrial membrane is essential for yeast cytochrome bc 1 complex function

Phosphatidylethanolamine (PE) is synthesized by four separate pathways, although surprisingly, perturbing mitochondrial PE synthesis compromises mitochondrial function. Here, the authors show that mitochondrial PE synthesis is required for Complex III function and challenge PE trafficking dogma.

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Autores principales:	Elizabeth Calzada, Erica Avery, Pingdewinde N. Sam, Arnab Modak, Chunyan Wang, J. Michael McCaffery, Xianlin Han, Nathan N. Alder, Steven M. Claypool
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ca5c4b849f3d4bd9ac4625fe961b2b19
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spelling	oai:doaj.org-article:ca5c4b849f3d4bd9ac4625fe961b2b192021-12-02T16:57:53ZPhosphatidylethanolamine made in the inner mitochondrial membrane is essential for yeast cytochrome bc 1 complex function10.1038/s41467-019-09425-12041-1723https://doaj.org/article/ca5c4b849f3d4bd9ac4625fe961b2b192019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09425-1https://doaj.org/toc/2041-1723Phosphatidylethanolamine (PE) is synthesized by four separate pathways, although surprisingly, perturbing mitochondrial PE synthesis compromises mitochondrial function. Here, the authors show that mitochondrial PE synthesis is required for Complex III function and challenge PE trafficking dogma.Elizabeth CalzadaErica AveryPingdewinde N. SamArnab ModakChunyan WangJ. Michael McCafferyXianlin HanNathan N. AlderSteven M. ClaypoolNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Elizabeth Calzada Erica Avery Pingdewinde N. Sam Arnab Modak Chunyan Wang J. Michael McCaffery Xianlin Han Nathan N. Alder Steven M. Claypool Phosphatidylethanolamine made in the inner mitochondrial membrane is essential for yeast cytochrome bc 1 complex function
description	Phosphatidylethanolamine (PE) is synthesized by four separate pathways, although surprisingly, perturbing mitochondrial PE synthesis compromises mitochondrial function. Here, the authors show that mitochondrial PE synthesis is required for Complex III function and challenge PE trafficking dogma.
format	article
author	Elizabeth Calzada Erica Avery Pingdewinde N. Sam Arnab Modak Chunyan Wang J. Michael McCaffery Xianlin Han Nathan N. Alder Steven M. Claypool
author_facet	Elizabeth Calzada Erica Avery Pingdewinde N. Sam Arnab Modak Chunyan Wang J. Michael McCaffery Xianlin Han Nathan N. Alder Steven M. Claypool
author_sort	Elizabeth Calzada
title	Phosphatidylethanolamine made in the inner mitochondrial membrane is essential for yeast cytochrome bc 1 complex function
title_short	Phosphatidylethanolamine made in the inner mitochondrial membrane is essential for yeast cytochrome bc 1 complex function
title_full	Phosphatidylethanolamine made in the inner mitochondrial membrane is essential for yeast cytochrome bc 1 complex function
title_fullStr	Phosphatidylethanolamine made in the inner mitochondrial membrane is essential for yeast cytochrome bc 1 complex function
title_full_unstemmed	Phosphatidylethanolamine made in the inner mitochondrial membrane is essential for yeast cytochrome bc 1 complex function
title_sort	phosphatidylethanolamine made in the inner mitochondrial membrane is essential for yeast cytochrome bc 1 complex function
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/ca5c4b849f3d4bd9ac4625fe961b2b19
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Phosphatidylethanolamine made in the inner mitochondrial membrane is essential for yeast cytochrome bc 1 complex function

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