Clinical Application of Silver Nanoparticles Coated by Benzalkonium Chloride

The present study investigates the surface modification of AgNPs (synthesized by neem leaves) by benzalkonium chloride (BAC). It was observed that 22 × 10<sup>9</sup> CFU were formed at 0.25 mM AgNPs concentration. However, it was reduced to 14 × 10<sup>9</sup> CFU for BAC-co...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Shakeel Ahmed Ansari, Asim Muhammed Alshanberi
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	antimicrobial green nanotechnology silver nanoparticles quaternary ammonium salts Engineering (General). Civil engineering (General) TA1-2040
Acceso en línea:	https://doaj.org/article/ca76573818df4e63add5e14745533bd7
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:ca76573818df4e63add5e14745533bd7
record_format	dspace
spelling	oai:doaj.org-article:ca76573818df4e63add5e14745533bd72021-11-25T17:16:41ZClinical Application of Silver Nanoparticles Coated by Benzalkonium Chloride10.3390/coatings111113822079-6412https://doaj.org/article/ca76573818df4e63add5e14745533bd72021-11-01T00:00:00Zhttps://www.mdpi.com/2079-6412/11/11/1382https://doaj.org/toc/2079-6412The present study investigates the surface modification of AgNPs (synthesized by neem leaves) by benzalkonium chloride (BAC). It was observed that 22 × 10<sup>9</sup> CFU were formed at 0.25 mM AgNPs concentration. However, it was reduced to 14 × 10<sup>9</sup> CFU for BAC-coated AgNPs at similar experimental conditions. The enzymatic activity of β-glucosidase was significantly enhanced from 0.0625 mM to 0.5 mM concentration of AgNPs, as well as BAC–AgNPs. However, there was no further change of activity beyond this concentration. ZOI of AgNPs and BAC–AgNPs was measured against <i>E. coli</i>, <i>B. subtilis</i>, <i>P. aeruginosa</i>, and <i>S pneumoniae</i> at 0.25 mM and 0.50 mM concentrations of these bioactive agents. ZOI was 3.45 cm and 3.56 cm for AgNPs and BAC–AgNPs at 0.25 mM of these bioactive agents, respectively, against <i>E. coli</i>. However, these values were 4.28 cm and 4.40 cm, respectively, against <i>B. subtilis</i>. ZOI was obtained at 3.36 cm and 3.47 cm, respectively, against <i>P. aeruginosa</i> under similar experimental concentrations. However, ZOI was achieved at 3.44 cm and 3.62 cm, respectively, against <i>S. pneumonia</i>, under similar experimental conditions. Hence, such research findings can be exploited for potential applications in numerous environmental and biomedical fields.Shakeel Ahmed AnsariAsim Muhammed AlshanberiMDPI AGarticleantimicrobialgreen nanotechnologysilver nanoparticlesquaternary ammonium saltsEngineering (General). Civil engineering (General)TA1-2040ENCoatings, Vol 11, Iss 1382, p 1382 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	antimicrobial green nanotechnology silver nanoparticles quaternary ammonium salts Engineering (General). Civil engineering (General) TA1-2040
spellingShingle	antimicrobial green nanotechnology silver nanoparticles quaternary ammonium salts Engineering (General). Civil engineering (General) TA1-2040 Shakeel Ahmed Ansari Asim Muhammed Alshanberi Clinical Application of Silver Nanoparticles Coated by Benzalkonium Chloride
description	The present study investigates the surface modification of AgNPs (synthesized by neem leaves) by benzalkonium chloride (BAC). It was observed that 22 × 10<sup>9</sup> CFU were formed at 0.25 mM AgNPs concentration. However, it was reduced to 14 × 10<sup>9</sup> CFU for BAC-coated AgNPs at similar experimental conditions. The enzymatic activity of β-glucosidase was significantly enhanced from 0.0625 mM to 0.5 mM concentration of AgNPs, as well as BAC–AgNPs. However, there was no further change of activity beyond this concentration. ZOI of AgNPs and BAC–AgNPs was measured against <i>E. coli</i>, <i>B. subtilis</i>, <i>P. aeruginosa</i>, and <i>S pneumoniae</i> at 0.25 mM and 0.50 mM concentrations of these bioactive agents. ZOI was 3.45 cm and 3.56 cm for AgNPs and BAC–AgNPs at 0.25 mM of these bioactive agents, respectively, against <i>E. coli</i>. However, these values were 4.28 cm and 4.40 cm, respectively, against <i>B. subtilis</i>. ZOI was obtained at 3.36 cm and 3.47 cm, respectively, against <i>P. aeruginosa</i> under similar experimental concentrations. However, ZOI was achieved at 3.44 cm and 3.62 cm, respectively, against <i>S. pneumonia</i>, under similar experimental conditions. Hence, such research findings can be exploited for potential applications in numerous environmental and biomedical fields.
format	article
author	Shakeel Ahmed Ansari Asim Muhammed Alshanberi
author_facet	Shakeel Ahmed Ansari Asim Muhammed Alshanberi
author_sort	Shakeel Ahmed Ansari
title	Clinical Application of Silver Nanoparticles Coated by Benzalkonium Chloride
title_short	Clinical Application of Silver Nanoparticles Coated by Benzalkonium Chloride
title_full	Clinical Application of Silver Nanoparticles Coated by Benzalkonium Chloride
title_fullStr	Clinical Application of Silver Nanoparticles Coated by Benzalkonium Chloride
title_full_unstemmed	Clinical Application of Silver Nanoparticles Coated by Benzalkonium Chloride
title_sort	clinical application of silver nanoparticles coated by benzalkonium chloride
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/ca76573818df4e63add5e14745533bd7
work_keys_str_mv	AT shakeelahmedansari clinicalapplicationofsilvernanoparticlescoatedbybenzalkoniumchloride AT asimmuhammedalshanberi clinicalapplicationofsilvernanoparticlescoatedbybenzalkoniumchloride
_version_	1718412558666301440

Clinical Application of Silver Nanoparticles Coated by Benzalkonium Chloride

Ejemplares similares