Cancer-Related Alopecia: From Etiologies to Global Management
Alopecia represents a multifaceted challenge with distinct etiologies and consequences. Transposed to the world of oncology, different types of alopecia and molecular pathways have been characterized, allowing a better understanding of the underlying mechanisms. In patients with cancer, alopecia can...
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2021
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oai:doaj.org-article:ca7a4a04910f4fc784e0497b269bd1aa2021-11-11T15:34:48ZCancer-Related Alopecia: From Etiologies to Global Management10.3390/cancers132155562072-6694https://doaj.org/article/ca7a4a04910f4fc784e0497b269bd1aa2021-11-01T00:00:00Zhttps://www.mdpi.com/2072-6694/13/21/5556https://doaj.org/toc/2072-6694Alopecia represents a multifaceted challenge with distinct etiologies and consequences. Transposed to the world of oncology, different types of alopecia and molecular pathways have been characterized, allowing a better understanding of the underlying mechanisms. In patients with cancer, alopecia can be iatrogenic (i.e., due to conventional chemotherapies, endocrine therapies, targeted therapies, immunotherapies, radiotherapy and surgery) or a direct consequence of the disease itself (e.g., malnutrition, scalp metastases and paraneoplastic syndromes). Identification of the actual incriminated mechanism(s) is therefore essential in order to deliver appropriate supportive care, whether preventive or curative. On the preventive side, the last few years have seen the advent of the automated cooling cap, a prophylactic approach supported by several randomized clinical trials. On the curative side, although the treatments currently available are limited, several promising therapeutic approaches are under development. Appropriate alopecia management is essential, particularly regarding its psychological repercussions with significant consequences on the quality of life of patients and their family and with a potential impact on treatment compliance.Stanislas QuesadaAlexandre GuichardFrédéric FiteniMDPI AGarticlealopeciasupportive carepsycho-oncologyquality of lifeNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENCancers, Vol 13, Iss 5556, p 5556 (2021) |
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alopecia supportive care psycho-oncology quality of life Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 |
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alopecia supportive care psycho-oncology quality of life Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Stanislas Quesada Alexandre Guichard Frédéric Fiteni Cancer-Related Alopecia: From Etiologies to Global Management |
description |
Alopecia represents a multifaceted challenge with distinct etiologies and consequences. Transposed to the world of oncology, different types of alopecia and molecular pathways have been characterized, allowing a better understanding of the underlying mechanisms. In patients with cancer, alopecia can be iatrogenic (i.e., due to conventional chemotherapies, endocrine therapies, targeted therapies, immunotherapies, radiotherapy and surgery) or a direct consequence of the disease itself (e.g., malnutrition, scalp metastases and paraneoplastic syndromes). Identification of the actual incriminated mechanism(s) is therefore essential in order to deliver appropriate supportive care, whether preventive or curative. On the preventive side, the last few years have seen the advent of the automated cooling cap, a prophylactic approach supported by several randomized clinical trials. On the curative side, although the treatments currently available are limited, several promising therapeutic approaches are under development. Appropriate alopecia management is essential, particularly regarding its psychological repercussions with significant consequences on the quality of life of patients and their family and with a potential impact on treatment compliance. |
format |
article |
author |
Stanislas Quesada Alexandre Guichard Frédéric Fiteni |
author_facet |
Stanislas Quesada Alexandre Guichard Frédéric Fiteni |
author_sort |
Stanislas Quesada |
title |
Cancer-Related Alopecia: From Etiologies to Global Management |
title_short |
Cancer-Related Alopecia: From Etiologies to Global Management |
title_full |
Cancer-Related Alopecia: From Etiologies to Global Management |
title_fullStr |
Cancer-Related Alopecia: From Etiologies to Global Management |
title_full_unstemmed |
Cancer-Related Alopecia: From Etiologies to Global Management |
title_sort |
cancer-related alopecia: from etiologies to global management |
publisher |
MDPI AG |
publishDate |
2021 |
url |
https://doaj.org/article/ca7a4a04910f4fc784e0497b269bd1aa |
work_keys_str_mv |
AT stanislasquesada cancerrelatedalopeciafrometiologiestoglobalmanagement AT alexandreguichard cancerrelatedalopeciafrometiologiestoglobalmanagement AT fredericfiteni cancerrelatedalopeciafrometiologiestoglobalmanagement |
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