Cancer-Related Alopecia: From Etiologies to Global Management

Alopecia represents a multifaceted challenge with distinct etiologies and consequences. Transposed to the world of oncology, different types of alopecia and molecular pathways have been characterized, allowing a better understanding of the underlying mechanisms. In patients with cancer, alopecia can...

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Autores principales: Stanislas Quesada, Alexandre Guichard, Frédéric Fiteni
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Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/ca7a4a04910f4fc784e0497b269bd1aa
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spelling oai:doaj.org-article:ca7a4a04910f4fc784e0497b269bd1aa2021-11-11T15:34:48ZCancer-Related Alopecia: From Etiologies to Global Management10.3390/cancers132155562072-6694https://doaj.org/article/ca7a4a04910f4fc784e0497b269bd1aa2021-11-01T00:00:00Zhttps://www.mdpi.com/2072-6694/13/21/5556https://doaj.org/toc/2072-6694Alopecia represents a multifaceted challenge with distinct etiologies and consequences. Transposed to the world of oncology, different types of alopecia and molecular pathways have been characterized, allowing a better understanding of the underlying mechanisms. In patients with cancer, alopecia can be iatrogenic (i.e., due to conventional chemotherapies, endocrine therapies, targeted therapies, immunotherapies, radiotherapy and surgery) or a direct consequence of the disease itself (e.g., malnutrition, scalp metastases and paraneoplastic syndromes). Identification of the actual incriminated mechanism(s) is therefore essential in order to deliver appropriate supportive care, whether preventive or curative. On the preventive side, the last few years have seen the advent of the automated cooling cap, a prophylactic approach supported by several randomized clinical trials. On the curative side, although the treatments currently available are limited, several promising therapeutic approaches are under development. Appropriate alopecia management is essential, particularly regarding its psychological repercussions with significant consequences on the quality of life of patients and their family and with a potential impact on treatment compliance.Stanislas QuesadaAlexandre GuichardFrédéric FiteniMDPI AGarticlealopeciasupportive carepsycho-oncologyquality of lifeNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENCancers, Vol 13, Iss 5556, p 5556 (2021)
institution DOAJ
collection DOAJ
language EN
topic alopecia
supportive care
psycho-oncology
quality of life
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
spellingShingle alopecia
supportive care
psycho-oncology
quality of life
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Stanislas Quesada
Alexandre Guichard
Frédéric Fiteni
Cancer-Related Alopecia: From Etiologies to Global Management
description Alopecia represents a multifaceted challenge with distinct etiologies and consequences. Transposed to the world of oncology, different types of alopecia and molecular pathways have been characterized, allowing a better understanding of the underlying mechanisms. In patients with cancer, alopecia can be iatrogenic (i.e., due to conventional chemotherapies, endocrine therapies, targeted therapies, immunotherapies, radiotherapy and surgery) or a direct consequence of the disease itself (e.g., malnutrition, scalp metastases and paraneoplastic syndromes). Identification of the actual incriminated mechanism(s) is therefore essential in order to deliver appropriate supportive care, whether preventive or curative. On the preventive side, the last few years have seen the advent of the automated cooling cap, a prophylactic approach supported by several randomized clinical trials. On the curative side, although the treatments currently available are limited, several promising therapeutic approaches are under development. Appropriate alopecia management is essential, particularly regarding its psychological repercussions with significant consequences on the quality of life of patients and their family and with a potential impact on treatment compliance.
format article
author Stanislas Quesada
Alexandre Guichard
Frédéric Fiteni
author_facet Stanislas Quesada
Alexandre Guichard
Frédéric Fiteni
author_sort Stanislas Quesada
title Cancer-Related Alopecia: From Etiologies to Global Management
title_short Cancer-Related Alopecia: From Etiologies to Global Management
title_full Cancer-Related Alopecia: From Etiologies to Global Management
title_fullStr Cancer-Related Alopecia: From Etiologies to Global Management
title_full_unstemmed Cancer-Related Alopecia: From Etiologies to Global Management
title_sort cancer-related alopecia: from etiologies to global management
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/ca7a4a04910f4fc784e0497b269bd1aa
work_keys_str_mv AT stanislasquesada cancerrelatedalopeciafrometiologiestoglobalmanagement
AT alexandreguichard cancerrelatedalopeciafrometiologiestoglobalmanagement
AT fredericfiteni cancerrelatedalopeciafrometiologiestoglobalmanagement
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