Surveillance of cohesin-supported chromosome structure controls meiotic progression

Meiosis-specific cohesins and the synaptonemal complex are essential for meiotic chromosome structure and function. Here the authors show that continued surveillance of these chromosome structures controls meiotic progression by regulating CHK-2, a master regulator of pairing and recombination.

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Autores principales: Maikel Castellano-Pozo, Sarai Pacheco, Georgios Sioutas, Angel Luis Jaso-Tamame, Marian H. Dore, Mohammad M. Karimi, Enrique Martinez-Perez
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/ca7beece05774737bac58f1c2cc21c92
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spelling oai:doaj.org-article:ca7beece05774737bac58f1c2cc21c922021-12-02T15:09:26ZSurveillance of cohesin-supported chromosome structure controls meiotic progression10.1038/s41467-020-18219-92041-1723https://doaj.org/article/ca7beece05774737bac58f1c2cc21c922020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18219-9https://doaj.org/toc/2041-1723Meiosis-specific cohesins and the synaptonemal complex are essential for meiotic chromosome structure and function. Here the authors show that continued surveillance of these chromosome structures controls meiotic progression by regulating CHK-2, a master regulator of pairing and recombination.Maikel Castellano-PozoSarai PachecoGeorgios SioutasAngel Luis Jaso-TamameMarian H. DoreMohammad M. KarimiEnrique Martinez-PerezNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Maikel Castellano-Pozo
Sarai Pacheco
Georgios Sioutas
Angel Luis Jaso-Tamame
Marian H. Dore
Mohammad M. Karimi
Enrique Martinez-Perez
Surveillance of cohesin-supported chromosome structure controls meiotic progression
description Meiosis-specific cohesins and the synaptonemal complex are essential for meiotic chromosome structure and function. Here the authors show that continued surveillance of these chromosome structures controls meiotic progression by regulating CHK-2, a master regulator of pairing and recombination.
format article
author Maikel Castellano-Pozo
Sarai Pacheco
Georgios Sioutas
Angel Luis Jaso-Tamame
Marian H. Dore
Mohammad M. Karimi
Enrique Martinez-Perez
author_facet Maikel Castellano-Pozo
Sarai Pacheco
Georgios Sioutas
Angel Luis Jaso-Tamame
Marian H. Dore
Mohammad M. Karimi
Enrique Martinez-Perez
author_sort Maikel Castellano-Pozo
title Surveillance of cohesin-supported chromosome structure controls meiotic progression
title_short Surveillance of cohesin-supported chromosome structure controls meiotic progression
title_full Surveillance of cohesin-supported chromosome structure controls meiotic progression
title_fullStr Surveillance of cohesin-supported chromosome structure controls meiotic progression
title_full_unstemmed Surveillance of cohesin-supported chromosome structure controls meiotic progression
title_sort surveillance of cohesin-supported chromosome structure controls meiotic progression
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/ca7beece05774737bac58f1c2cc21c92
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