Surveillance of cohesin-supported chromosome structure controls meiotic progression
Meiosis-specific cohesins and the synaptonemal complex are essential for meiotic chromosome structure and function. Here the authors show that continued surveillance of these chromosome structures controls meiotic progression by regulating CHK-2, a master regulator of pairing and recombination.
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Nature Portfolio
2020
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oai:doaj.org-article:ca7beece05774737bac58f1c2cc21c922021-12-02T15:09:26ZSurveillance of cohesin-supported chromosome structure controls meiotic progression10.1038/s41467-020-18219-92041-1723https://doaj.org/article/ca7beece05774737bac58f1c2cc21c922020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18219-9https://doaj.org/toc/2041-1723Meiosis-specific cohesins and the synaptonemal complex are essential for meiotic chromosome structure and function. Here the authors show that continued surveillance of these chromosome structures controls meiotic progression by regulating CHK-2, a master regulator of pairing and recombination.Maikel Castellano-PozoSarai PachecoGeorgios SioutasAngel Luis Jaso-TamameMarian H. DoreMohammad M. KarimiEnrique Martinez-PerezNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020) |
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Science Q Maikel Castellano-Pozo Sarai Pacheco Georgios Sioutas Angel Luis Jaso-Tamame Marian H. Dore Mohammad M. Karimi Enrique Martinez-Perez Surveillance of cohesin-supported chromosome structure controls meiotic progression |
description |
Meiosis-specific cohesins and the synaptonemal complex are essential for meiotic chromosome structure and function. Here the authors show that continued surveillance of these chromosome structures controls meiotic progression by regulating CHK-2, a master regulator of pairing and recombination. |
format |
article |
author |
Maikel Castellano-Pozo Sarai Pacheco Georgios Sioutas Angel Luis Jaso-Tamame Marian H. Dore Mohammad M. Karimi Enrique Martinez-Perez |
author_facet |
Maikel Castellano-Pozo Sarai Pacheco Georgios Sioutas Angel Luis Jaso-Tamame Marian H. Dore Mohammad M. Karimi Enrique Martinez-Perez |
author_sort |
Maikel Castellano-Pozo |
title |
Surveillance of cohesin-supported chromosome structure controls meiotic progression |
title_short |
Surveillance of cohesin-supported chromosome structure controls meiotic progression |
title_full |
Surveillance of cohesin-supported chromosome structure controls meiotic progression |
title_fullStr |
Surveillance of cohesin-supported chromosome structure controls meiotic progression |
title_full_unstemmed |
Surveillance of cohesin-supported chromosome structure controls meiotic progression |
title_sort |
surveillance of cohesin-supported chromosome structure controls meiotic progression |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/ca7beece05774737bac58f1c2cc21c92 |
work_keys_str_mv |
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1718387839489540096 |