Intracameral vancomycin following cataract surgery: An eleven-year study

Deepa R Anijeet, Prasad Palimar, Clive O PeckarDepartment of Ophthalmology, Warrington and Halton NHS Trust, UKAim: To compare the incidences of endophthalmitis after cataract operations before and after introduction of intracameral vancomycin at the end of surgery.Methods: A retrospective analysis...

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Autores principales:	Deepa R Anijeet, Prasad Palimar, Clive O Peckar
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/ca8421598b904292ac3e1a9c442226f9
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spelling	oai:doaj.org-article:ca8421598b904292ac3e1a9c442226f92021-12-02T04:28:54ZIntracameral vancomycin following cataract surgery: An eleven-year study1177-54671177-5483https://doaj.org/article/ca8421598b904292ac3e1a9c442226f92010-04-01T00:00:00Zhttp://www.dovepress.com/intracameral-vancomycin-following-cataract-surgery-an-eleven-year-stud-a4289https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Deepa R Anijeet, Prasad Palimar, Clive O PeckarDepartment of Ophthalmology, Warrington and Halton NHS Trust, UKAim: To compare the incidences of endophthalmitis after cataract operations before and after introduction of intracameral vancomycin at the end of surgery.Methods: A retrospective analysis was performed of presumed infectious endophthalmitis after cataract surgery from January 1, 1998 to December 31, 2008. From January 2001, the practice of using intracameral vancomycin at the end of cataract surgery was introduced. The period before introduction of intracameral vancomycin is considered as period A and that after as period B. The incidences of presumed or culture-proven endophthalmitis during periods A and B were compared.Results: A total of 16,606 cataract surgeries were performed during the study period. The incidence of endophthalmitis per 1000 cataract surgeries was 3.0 during period A and 0.08 during period B. This reduction was statistically significantly (Chi-squared test 36.6, P value &lt; 0.0001). The relative risk of developing endophthalmitis without intracameral vancomycin prophylaxis was 38. The absolute risk reduction was 292 cases of endophthalmitis per 100,000 cataract surgeries.Conclusions: Intracameral vancomycin significantly reduced the incidence of postoperative endophthalmitis after cataract surgery. There is a universal need to adopt this mode of microbial prophylaxis to reduce the burden of endophthalmitis after cataract surgery.Keywords: endophthalmitis, intracameral vancomycin, cataract surgery Deepa R AnijeetPrasad PalimarClive O PeckarDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2010, Iss default, Pp 321-326 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Deepa R Anijeet Prasad Palimar Clive O Peckar Intracameral vancomycin following cataract surgery: An eleven-year study
description	Deepa R Anijeet, Prasad Palimar, Clive O PeckarDepartment of Ophthalmology, Warrington and Halton NHS Trust, UKAim: To compare the incidences of endophthalmitis after cataract operations before and after introduction of intracameral vancomycin at the end of surgery.Methods: A retrospective analysis was performed of presumed infectious endophthalmitis after cataract surgery from January 1, 1998 to December 31, 2008. From January 2001, the practice of using intracameral vancomycin at the end of cataract surgery was introduced. The period before introduction of intracameral vancomycin is considered as period A and that after as period B. The incidences of presumed or culture-proven endophthalmitis during periods A and B were compared.Results: A total of 16,606 cataract surgeries were performed during the study period. The incidence of endophthalmitis per 1000 cataract surgeries was 3.0 during period A and 0.08 during period B. This reduction was statistically significantly (Chi-squared test 36.6, P value &lt; 0.0001). The relative risk of developing endophthalmitis without intracameral vancomycin prophylaxis was 38. The absolute risk reduction was 292 cases of endophthalmitis per 100,000 cataract surgeries.Conclusions: Intracameral vancomycin significantly reduced the incidence of postoperative endophthalmitis after cataract surgery. There is a universal need to adopt this mode of microbial prophylaxis to reduce the burden of endophthalmitis after cataract surgery.Keywords: endophthalmitis, intracameral vancomycin, cataract surgery
format	article
author	Deepa R Anijeet Prasad Palimar Clive O Peckar
author_facet	Deepa R Anijeet Prasad Palimar Clive O Peckar
author_sort	Deepa R Anijeet
title	Intracameral vancomycin following cataract surgery: An eleven-year study
title_short	Intracameral vancomycin following cataract surgery: An eleven-year study
title_full	Intracameral vancomycin following cataract surgery: An eleven-year study
title_fullStr	Intracameral vancomycin following cataract surgery: An eleven-year study
title_full_unstemmed	Intracameral vancomycin following cataract surgery: An eleven-year study
title_sort	intracameral vancomycin following cataract surgery: an eleven-year study
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/ca8421598b904292ac3e1a9c442226f9
work_keys_str_mv	AT deeparanijeet intracameralvancomycinfollowingcataractsurgeryanelevenyearstudy AT prasadpalimar intracameralvancomycinfollowingcataractsurgeryanelevenyearstudy AT cliveopeckar intracameralvancomycinfollowingcataractsurgeryanelevenyearstudy
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Intracameral vancomycin following cataract surgery: An eleven-year study

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