Wolbachia divergence and the evolution of cytoplasmic incompatibility in Culex pipiens.

Many insect species harbor Wolbachia bacteria that induce cytoplasmic incompatibility (CI), i.e. embryonic lethality in crosses between infected males and uninfected females, or between males and females carrying incompatible Wolbachia strains. The molecular mechanism of CI remains unknown, but the...

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Autores principales:	Célestine M Atyame, Pierrick Labbé, Emilie Dumas, Pascal Milesi, Sylvain Charlat, Philippe Fort, Mylène Weill
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2014
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/ca9446a101e9456cb13e26b01bfd6f73
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spelling	oai:doaj.org-article:ca9446a101e9456cb13e26b01bfd6f732021-11-18T08:34:35ZWolbachia divergence and the evolution of cytoplasmic incompatibility in Culex pipiens.1932-620310.1371/journal.pone.0087336https://doaj.org/article/ca9446a101e9456cb13e26b01bfd6f732014-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24498078/?tool=EBIhttps://doaj.org/toc/1932-6203Many insect species harbor Wolbachia bacteria that induce cytoplasmic incompatibility (CI), i.e. embryonic lethality in crosses between infected males and uninfected females, or between males and females carrying incompatible Wolbachia strains. The molecular mechanism of CI remains unknown, but the available data are best interpreted under a modification-rescue model, where a mod function disables the reproductive success of infected males' sperm, unless the eggs are infected and express a compatible resc function. Here we examine the evolution of CI in the mosquito Culex pipiens, harbouring a large number of closely related Wolbachia strains structured in five distinct phylogenetic groups. Specifically, we used a worldwide sample of mosquito lines to assess the hypothesis that genetic divergence should correlate with the divergence of CI properties on a low evolutionary scale. We observed a significant association of Wolbachia genetic divergence with CI patterns. Most Wolbachia strains from the same group were compatible whereas those from different groups were often incompatible. Consistently, we found a strong association between Wolbachia groups and their mod-resc properties. Finally, lines from the same geographical area were rarely incompatible, confirming the conjecture that the spatial distribution of Wolbachia compatibility types should be constrained by selection. This study indicates a clear correlation between Wolbachia genotypes and CI properties, paving the way toward the identification of the molecular basis of CI through comparative genomics.Célestine M AtyamePierrick LabbéEmilie DumasPascal MilesiSylvain CharlatPhilippe FortMylène WeillPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 1, p e87336 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Célestine M Atyame Pierrick Labbé Emilie Dumas Pascal Milesi Sylvain Charlat Philippe Fort Mylène Weill Wolbachia divergence and the evolution of cytoplasmic incompatibility in Culex pipiens.
description	Many insect species harbor Wolbachia bacteria that induce cytoplasmic incompatibility (CI), i.e. embryonic lethality in crosses between infected males and uninfected females, or between males and females carrying incompatible Wolbachia strains. The molecular mechanism of CI remains unknown, but the available data are best interpreted under a modification-rescue model, where a mod function disables the reproductive success of infected males' sperm, unless the eggs are infected and express a compatible resc function. Here we examine the evolution of CI in the mosquito Culex pipiens, harbouring a large number of closely related Wolbachia strains structured in five distinct phylogenetic groups. Specifically, we used a worldwide sample of mosquito lines to assess the hypothesis that genetic divergence should correlate with the divergence of CI properties on a low evolutionary scale. We observed a significant association of Wolbachia genetic divergence with CI patterns. Most Wolbachia strains from the same group were compatible whereas those from different groups were often incompatible. Consistently, we found a strong association between Wolbachia groups and their mod-resc properties. Finally, lines from the same geographical area were rarely incompatible, confirming the conjecture that the spatial distribution of Wolbachia compatibility types should be constrained by selection. This study indicates a clear correlation between Wolbachia genotypes and CI properties, paving the way toward the identification of the molecular basis of CI through comparative genomics.
format	article
author	Célestine M Atyame Pierrick Labbé Emilie Dumas Pascal Milesi Sylvain Charlat Philippe Fort Mylène Weill
author_facet	Célestine M Atyame Pierrick Labbé Emilie Dumas Pascal Milesi Sylvain Charlat Philippe Fort Mylène Weill
author_sort	Célestine M Atyame
title	Wolbachia divergence and the evolution of cytoplasmic incompatibility in Culex pipiens.
title_short	Wolbachia divergence and the evolution of cytoplasmic incompatibility in Culex pipiens.
title_full	Wolbachia divergence and the evolution of cytoplasmic incompatibility in Culex pipiens.
title_fullStr	Wolbachia divergence and the evolution of cytoplasmic incompatibility in Culex pipiens.
title_full_unstemmed	Wolbachia divergence and the evolution of cytoplasmic incompatibility in Culex pipiens.
title_sort	wolbachia divergence and the evolution of cytoplasmic incompatibility in culex pipiens.
publisher	Public Library of Science (PLoS)
publishDate	2014
url	https://doaj.org/article/ca9446a101e9456cb13e26b01bfd6f73
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Wolbachia divergence and the evolution of cytoplasmic incompatibility in Culex pipiens.

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