Parabrachial nucleus circuit governs neuropathic pain-like behavior

The parabrachial nucleus (PBN) projects to the amygdala, and contributes to affective aspects of neuropathic pain. Here the authors demonstrate that the lateral parabrachial nucleus (LPBN) contributes to hypersensitivity in a mouse model of neuropathic pain.

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Detalles Bibliográficos
Autores principales: Li Sun, Rui Liu, Fang Guo, Man-qing Wen, Xiao-lin Ma, Kai-yuan Li, Hao Sun, Ceng-lin Xu, Yuan-yuan Li, Meng-yin Wu, Zheng-gang Zhu, Xin-jian Li, Yan-qin Yu, Zhong Chen, Xiang-yao Li, Shumin Duan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/ca966f8a0369483dafb67a92447ca6e3
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Descripción
Sumario:The parabrachial nucleus (PBN) projects to the amygdala, and contributes to affective aspects of neuropathic pain. Here the authors demonstrate that the lateral parabrachial nucleus (LPBN) contributes to hypersensitivity in a mouse model of neuropathic pain.