Parabrachial nucleus circuit governs neuropathic pain-like behavior

The parabrachial nucleus (PBN) projects to the amygdala, and contributes to affective aspects of neuropathic pain. Here the authors demonstrate that the lateral parabrachial nucleus (LPBN) contributes to hypersensitivity in a mouse model of neuropathic pain.

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Autores principales: Li Sun, Rui Liu, Fang Guo, Man-qing Wen, Xiao-lin Ma, Kai-yuan Li, Hao Sun, Ceng-lin Xu, Yuan-yuan Li, Meng-yin Wu, Zheng-gang Zhu, Xin-jian Li, Yan-qin Yu, Zhong Chen, Xiang-yao Li, Shumin Duan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/ca966f8a0369483dafb67a92447ca6e3
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spelling oai:doaj.org-article:ca966f8a0369483dafb67a92447ca6e32021-12-02T13:24:15ZParabrachial nucleus circuit governs neuropathic pain-like behavior10.1038/s41467-020-19767-w2041-1723https://doaj.org/article/ca966f8a0369483dafb67a92447ca6e32020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19767-whttps://doaj.org/toc/2041-1723The parabrachial nucleus (PBN) projects to the amygdala, and contributes to affective aspects of neuropathic pain. Here the authors demonstrate that the lateral parabrachial nucleus (LPBN) contributes to hypersensitivity in a mouse model of neuropathic pain.Li SunRui LiuFang GuoMan-qing WenXiao-lin MaKai-yuan LiHao SunCeng-lin XuYuan-yuan LiMeng-yin WuZheng-gang ZhuXin-jian LiYan-qin YuZhong ChenXiang-yao LiShumin DuanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Li Sun
Rui Liu
Fang Guo
Man-qing Wen
Xiao-lin Ma
Kai-yuan Li
Hao Sun
Ceng-lin Xu
Yuan-yuan Li
Meng-yin Wu
Zheng-gang Zhu
Xin-jian Li
Yan-qin Yu
Zhong Chen
Xiang-yao Li
Shumin Duan
Parabrachial nucleus circuit governs neuropathic pain-like behavior
description The parabrachial nucleus (PBN) projects to the amygdala, and contributes to affective aspects of neuropathic pain. Here the authors demonstrate that the lateral parabrachial nucleus (LPBN) contributes to hypersensitivity in a mouse model of neuropathic pain.
format article
author Li Sun
Rui Liu
Fang Guo
Man-qing Wen
Xiao-lin Ma
Kai-yuan Li
Hao Sun
Ceng-lin Xu
Yuan-yuan Li
Meng-yin Wu
Zheng-gang Zhu
Xin-jian Li
Yan-qin Yu
Zhong Chen
Xiang-yao Li
Shumin Duan
author_facet Li Sun
Rui Liu
Fang Guo
Man-qing Wen
Xiao-lin Ma
Kai-yuan Li
Hao Sun
Ceng-lin Xu
Yuan-yuan Li
Meng-yin Wu
Zheng-gang Zhu
Xin-jian Li
Yan-qin Yu
Zhong Chen
Xiang-yao Li
Shumin Duan
author_sort Li Sun
title Parabrachial nucleus circuit governs neuropathic pain-like behavior
title_short Parabrachial nucleus circuit governs neuropathic pain-like behavior
title_full Parabrachial nucleus circuit governs neuropathic pain-like behavior
title_fullStr Parabrachial nucleus circuit governs neuropathic pain-like behavior
title_full_unstemmed Parabrachial nucleus circuit governs neuropathic pain-like behavior
title_sort parabrachial nucleus circuit governs neuropathic pain-like behavior
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/ca966f8a0369483dafb67a92447ca6e3
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