Clinical significance of increased arterial stiffness associated with atrial fibrillation, according to Framingham risk score

Abstract Atrial fibrillation (AF) is the most common arrhythmia in the elderly. Arterial stiffness may predict the risk of AF, but this relationship has not been fully evaluated. We assessed the association between arterial stiffness and prevalent AF. All subjects who had electrocardiography perform...

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Autores principales:	Goh Eun Chung, Hyo Eun Park, Heesun Lee, Su-Yeon Choi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/ca9f19aef56c419186330e9bae5f3b14
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spelling	oai:doaj.org-article:ca9f19aef56c419186330e9bae5f3b142021-12-02T13:19:23ZClinical significance of increased arterial stiffness associated with atrial fibrillation, according to Framingham risk score10.1038/s41598-021-84311-92045-2322https://doaj.org/article/ca9f19aef56c419186330e9bae5f3b142021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-84311-9https://doaj.org/toc/2045-2322Abstract Atrial fibrillation (AF) is the most common arrhythmia in the elderly. Arterial stiffness may predict the risk of AF, but this relationship has not been fully evaluated. We assessed the association between arterial stiffness and prevalent AF. All subjects who had electrocardiography performed and a cardio-ankle vascular index (CAVI) calculated during a screening examination between 2010 and 2019 were enrolled. To evaluate the association between increased arterial stiffness and AF, we divided the population according to their Framingham risk score (FRS) into low-, intermediate-, and high-risk groups. A total of 8048 subjects were evaluated. The multivariate analysis revealed that increased arterial stiffness was significantly associated with AF prevalence, even after adjusting cardiovascular risk factors [odds ratio (OR) 1.685, 95% confidence interval (CI) 1.908–2.588, p = 0.017]. When we subcategorized the subjects according to their FRS, increased arterial stiffness was significantly associated with AF in the intermediate- and high-risk groups (OR 3.062, 95% CI 1.39-6.740 and OR3.877, 95% CI 1.142-13.167, respectively, BMI adjusted. High arterial stiffness shows a significant association with AF in those with intermediate or high cardiovascular risk, and can be used for further risk stratification of patients.Goh Eun ChungHyo Eun ParkHeesun LeeSu-Yeon ChoiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Goh Eun Chung Hyo Eun Park Heesun Lee Su-Yeon Choi Clinical significance of increased arterial stiffness associated with atrial fibrillation, according to Framingham risk score
description	Abstract Atrial fibrillation (AF) is the most common arrhythmia in the elderly. Arterial stiffness may predict the risk of AF, but this relationship has not been fully evaluated. We assessed the association between arterial stiffness and prevalent AF. All subjects who had electrocardiography performed and a cardio-ankle vascular index (CAVI) calculated during a screening examination between 2010 and 2019 were enrolled. To evaluate the association between increased arterial stiffness and AF, we divided the population according to their Framingham risk score (FRS) into low-, intermediate-, and high-risk groups. A total of 8048 subjects were evaluated. The multivariate analysis revealed that increased arterial stiffness was significantly associated with AF prevalence, even after adjusting cardiovascular risk factors [odds ratio (OR) 1.685, 95% confidence interval (CI) 1.908–2.588, p = 0.017]. When we subcategorized the subjects according to their FRS, increased arterial stiffness was significantly associated with AF in the intermediate- and high-risk groups (OR 3.062, 95% CI 1.39-6.740 and OR3.877, 95% CI 1.142-13.167, respectively, BMI adjusted. High arterial stiffness shows a significant association with AF in those with intermediate or high cardiovascular risk, and can be used for further risk stratification of patients.
format	article
author	Goh Eun Chung Hyo Eun Park Heesun Lee Su-Yeon Choi
author_facet	Goh Eun Chung Hyo Eun Park Heesun Lee Su-Yeon Choi
author_sort	Goh Eun Chung
title	Clinical significance of increased arterial stiffness associated with atrial fibrillation, according to Framingham risk score
title_short	Clinical significance of increased arterial stiffness associated with atrial fibrillation, according to Framingham risk score
title_full	Clinical significance of increased arterial stiffness associated with atrial fibrillation, according to Framingham risk score
title_fullStr	Clinical significance of increased arterial stiffness associated with atrial fibrillation, according to Framingham risk score
title_full_unstemmed	Clinical significance of increased arterial stiffness associated with atrial fibrillation, according to Framingham risk score
title_sort	clinical significance of increased arterial stiffness associated with atrial fibrillation, according to framingham risk score
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/ca9f19aef56c419186330e9bae5f3b14
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Clinical significance of increased arterial stiffness associated with atrial fibrillation, according to Framingham risk score

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