Inhibition of the PERK/TXNIP/NLRP3 Axis by Baicalin Reduces NLRP3 Inflammasome-Mediated Pyroptosis in Macrophages Infected with Mycobacterium tuberculosis
Mycobacterium tuberculosis (Mtb) remains a significant threat to global health as it induces granuloma and systemic inflammatory responses during active tuberculosis. Mtb can induce macrophage pyroptosis, leading to the release of IL-1β and tissue damage, promoting its spread. Here, we established a...
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| Auteurs principaux: | , , , , , , |
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| Format: | article |
| Langue: | EN |
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Hindawi Limited
2021
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| Accès en ligne: | https://doaj.org/article/caa51d5f5aae48569a78b0279f820324 |
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