Hyperuricemia and clustering of cardiovascular risk factors in the Chinese adult population
Abstract Hyperuricemia is common in China and the relevance of hyperuricemia and cardiovascular disease (CVD) risk has been highlighted, but to date there has been rarely nation-wide study in China. Here, we aim to estimate the current prevalence of hyperuricemia and evaluate the associations betwee...
Guardado en:
| Autores principales: | , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2017
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/caa8eca3e3f44b48b2219813f1e005fb |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:caa8eca3e3f44b48b2219813f1e005fb |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:caa8eca3e3f44b48b2219813f1e005fb2021-12-02T16:06:11ZHyperuricemia and clustering of cardiovascular risk factors in the Chinese adult population10.1038/s41598-017-05751-w2045-2322https://doaj.org/article/caa8eca3e3f44b48b2219813f1e005fb2017-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-05751-whttps://doaj.org/toc/2045-2322Abstract Hyperuricemia is common in China and the relevance of hyperuricemia and cardiovascular disease (CVD) risk has been highlighted, but to date there has been rarely nation-wide study in China. Here, we aim to estimate the current prevalence of hyperuricemia and evaluate the associations between hyperuricemia and cardiovascular risk factors (CRFs) clustering in a large sample of China adults including a plurality of ethnic minorities. Generally, a nationally representative sample of 22983 adults aged ≥18 years was recruited from 2007 to 2011. Questionnaire data and information on anthropometric characteristics, and laboratory measurements were collected. We define hyperuricemia as SUA ≥416 mmol/L for men and SUA ≥357 mmol/L for women. We found that the prevalence of hyperuricemia was 13.0% (18.5% in men and 8.0% in women). To our estimation, hyperuricemic subjects had higher prevalence rates of CRFs clustering than non-hyperuricemic subjects. Furthermore, there was a dose-response association between the number of CVD risk factors clustering and hyperuricemia. Our study revealed a high prevalence of hyperuricemia and CVD risk factors clustering among Chinese adults, and hyperuricemia was significantly associated with coexistence of more CVD risk factors. Therefore, guidance and effective lifestyle intervention are required to prevent hyperuricemia and CVD risk factors in China.Jie WuLing QiuXin-qi ChengTao XuWei WuXue-jun ZengYi-cong YeXiu-zhi GuoQian ChengQian LiuLi LiuCheng-li XuGuang-jin ZhuNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-8 (2017) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Medicine R Science Q |
| spellingShingle |
Medicine R Science Q Jie Wu Ling Qiu Xin-qi Cheng Tao Xu Wei Wu Xue-jun Zeng Yi-cong Ye Xiu-zhi Guo Qian Cheng Qian Liu Li Liu Cheng-li Xu Guang-jin Zhu Hyperuricemia and clustering of cardiovascular risk factors in the Chinese adult population |
| description |
Abstract Hyperuricemia is common in China and the relevance of hyperuricemia and cardiovascular disease (CVD) risk has been highlighted, but to date there has been rarely nation-wide study in China. Here, we aim to estimate the current prevalence of hyperuricemia and evaluate the associations between hyperuricemia and cardiovascular risk factors (CRFs) clustering in a large sample of China adults including a plurality of ethnic minorities. Generally, a nationally representative sample of 22983 adults aged ≥18 years was recruited from 2007 to 2011. Questionnaire data and information on anthropometric characteristics, and laboratory measurements were collected. We define hyperuricemia as SUA ≥416 mmol/L for men and SUA ≥357 mmol/L for women. We found that the prevalence of hyperuricemia was 13.0% (18.5% in men and 8.0% in women). To our estimation, hyperuricemic subjects had higher prevalence rates of CRFs clustering than non-hyperuricemic subjects. Furthermore, there was a dose-response association between the number of CVD risk factors clustering and hyperuricemia. Our study revealed a high prevalence of hyperuricemia and CVD risk factors clustering among Chinese adults, and hyperuricemia was significantly associated with coexistence of more CVD risk factors. Therefore, guidance and effective lifestyle intervention are required to prevent hyperuricemia and CVD risk factors in China. |
| format |
article |
| author |
Jie Wu Ling Qiu Xin-qi Cheng Tao Xu Wei Wu Xue-jun Zeng Yi-cong Ye Xiu-zhi Guo Qian Cheng Qian Liu Li Liu Cheng-li Xu Guang-jin Zhu |
| author_facet |
Jie Wu Ling Qiu Xin-qi Cheng Tao Xu Wei Wu Xue-jun Zeng Yi-cong Ye Xiu-zhi Guo Qian Cheng Qian Liu Li Liu Cheng-li Xu Guang-jin Zhu |
| author_sort |
Jie Wu |
| title |
Hyperuricemia and clustering of cardiovascular risk factors in the Chinese adult population |
| title_short |
Hyperuricemia and clustering of cardiovascular risk factors in the Chinese adult population |
| title_full |
Hyperuricemia and clustering of cardiovascular risk factors in the Chinese adult population |
| title_fullStr |
Hyperuricemia and clustering of cardiovascular risk factors in the Chinese adult population |
| title_full_unstemmed |
Hyperuricemia and clustering of cardiovascular risk factors in the Chinese adult population |
| title_sort |
hyperuricemia and clustering of cardiovascular risk factors in the chinese adult population |
| publisher |
Nature Portfolio |
| publishDate |
2017 |
| url |
https://doaj.org/article/caa8eca3e3f44b48b2219813f1e005fb |
| work_keys_str_mv |
AT jiewu hyperuricemiaandclusteringofcardiovascularriskfactorsinthechineseadultpopulation AT lingqiu hyperuricemiaandclusteringofcardiovascularriskfactorsinthechineseadultpopulation AT xinqicheng hyperuricemiaandclusteringofcardiovascularriskfactorsinthechineseadultpopulation AT taoxu hyperuricemiaandclusteringofcardiovascularriskfactorsinthechineseadultpopulation AT weiwu hyperuricemiaandclusteringofcardiovascularriskfactorsinthechineseadultpopulation AT xuejunzeng hyperuricemiaandclusteringofcardiovascularriskfactorsinthechineseadultpopulation AT yicongye hyperuricemiaandclusteringofcardiovascularriskfactorsinthechineseadultpopulation AT xiuzhiguo hyperuricemiaandclusteringofcardiovascularriskfactorsinthechineseadultpopulation AT qiancheng hyperuricemiaandclusteringofcardiovascularriskfactorsinthechineseadultpopulation AT qianliu hyperuricemiaandclusteringofcardiovascularriskfactorsinthechineseadultpopulation AT liliu hyperuricemiaandclusteringofcardiovascularriskfactorsinthechineseadultpopulation AT chenglixu hyperuricemiaandclusteringofcardiovascularriskfactorsinthechineseadultpopulation AT guangjinzhu hyperuricemiaandclusteringofcardiovascularriskfactorsinthechineseadultpopulation |
| _version_ |
1718385114237370368 |