Synthesis, characterization, applications, and challenges of iron oxide nanoparticles

Attarad Ali,1 Hira Zafar,1 Muhammad Zia,1 Ihsan ul Haq,2 Abdul Rehman Phull,3 Joham Sarfraz Ali,1 Altaf Hussain4 1Department of Biotechnology, 2Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan; 3Department of Biology, Kongju National University, Kongju, South Korea; 4Department o...

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Autores principales: Ali A, Zafar H, Zia M, ul Haq I, Phull AR, Ali JS, Hussain A
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Publicado: Dove Medical Press 2016
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spelling oai:doaj.org-article:caaf9c49d0bf4a13932ddcbd4bb9fee52021-12-02T06:30:38ZSynthesis, characterization, applications, and challenges of iron oxide nanoparticles1177-8903https://doaj.org/article/caaf9c49d0bf4a13932ddcbd4bb9fee52016-08-01T00:00:00Zhttps://www.dovepress.com/synthesis-characterization-applications-and-challenges-of-iron-oxide-n-peer-reviewed-article-NSAhttps://doaj.org/toc/1177-8903Attarad Ali,1 Hira Zafar,1 Muhammad Zia,1 Ihsan ul Haq,2 Abdul Rehman Phull,3 Joham Sarfraz Ali,1 Altaf Hussain4 1Department of Biotechnology, 2Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan; 3Department of Biology, Kongju National University, Kongju, South Korea; 4Department of Materials Science and Engineering, Institute of Space Technology, Islamabad, Pakistan Abstract: Recently, iron oxide nanoparticles (NPs) have attracted much consideration due to their unique properties, such as superparamagnetism, surface-to-volume ratio, greater surface area, and easy separation methodology. Various physical, chemical, and biological methods have been adopted to synthesize magnetic NPs with suitable surface chemistry. This review summarizes the methods for the preparation of iron oxide NPs, size and morphology control, and magnetic properties with recent bioengineering, commercial, and industrial applications. Iron oxides exhibit great potential in the fields of life sciences such as biomedicine, agriculture, and environment. Nontoxic conduct and biocompatible applications of magnetic NPs can be enriched further by special surface coating with organic or inorganic molecules, including surfactants, drugs, proteins, starches, enzymes, antibodies, nucleotides, nonionic detergents, and polyelectrolytes. Magnetic NPs can also be directed to an organ, tissue, or tumor using an external magnetic field for hyperthermic treatment of patients. Keeping in mind the current interest in iron NPs, this review is designed to report recent information from synthesis to characterization, and applications of iron NPs. Keywords: superparamagnetism, iron oxide nanoparticles, surfactants, hyperthermia, biodistribution, bioeliminationAli AZafar HZia Mul Haq IPhull ARAli JSHussain ADove Medical PressarticleSuper-ParamagnetismIron Oxide Nano ParticlesSurfactantsHyperthermiaBiodistributionBioeliminationMedical technologyR855-855.5Chemical technologyTP1-1185ENNanotechnology, Science and Applications, Vol Volume 9, Pp 49-67 (2016)
institution DOAJ
collection DOAJ
language EN
topic Super-Paramagnetism
Iron Oxide Nano Particles
Surfactants
Hyperthermia
Biodistribution
Bioelimination
Medical technology
R855-855.5
Chemical technology
TP1-1185
spellingShingle Super-Paramagnetism
Iron Oxide Nano Particles
Surfactants
Hyperthermia
Biodistribution
Bioelimination
Medical technology
R855-855.5
Chemical technology
TP1-1185
Ali A
Zafar H
Zia M
ul Haq I
Phull AR
Ali JS
Hussain A
Synthesis, characterization, applications, and challenges of iron oxide nanoparticles
description Attarad Ali,1 Hira Zafar,1 Muhammad Zia,1 Ihsan ul Haq,2 Abdul Rehman Phull,3 Joham Sarfraz Ali,1 Altaf Hussain4 1Department of Biotechnology, 2Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan; 3Department of Biology, Kongju National University, Kongju, South Korea; 4Department of Materials Science and Engineering, Institute of Space Technology, Islamabad, Pakistan Abstract: Recently, iron oxide nanoparticles (NPs) have attracted much consideration due to their unique properties, such as superparamagnetism, surface-to-volume ratio, greater surface area, and easy separation methodology. Various physical, chemical, and biological methods have been adopted to synthesize magnetic NPs with suitable surface chemistry. This review summarizes the methods for the preparation of iron oxide NPs, size and morphology control, and magnetic properties with recent bioengineering, commercial, and industrial applications. Iron oxides exhibit great potential in the fields of life sciences such as biomedicine, agriculture, and environment. Nontoxic conduct and biocompatible applications of magnetic NPs can be enriched further by special surface coating with organic or inorganic molecules, including surfactants, drugs, proteins, starches, enzymes, antibodies, nucleotides, nonionic detergents, and polyelectrolytes. Magnetic NPs can also be directed to an organ, tissue, or tumor using an external magnetic field for hyperthermic treatment of patients. Keeping in mind the current interest in iron NPs, this review is designed to report recent information from synthesis to characterization, and applications of iron NPs. Keywords: superparamagnetism, iron oxide nanoparticles, surfactants, hyperthermia, biodistribution, bioelimination
format article
author Ali A
Zafar H
Zia M
ul Haq I
Phull AR
Ali JS
Hussain A
author_facet Ali A
Zafar H
Zia M
ul Haq I
Phull AR
Ali JS
Hussain A
author_sort Ali A
title Synthesis, characterization, applications, and challenges of iron oxide nanoparticles
title_short Synthesis, characterization, applications, and challenges of iron oxide nanoparticles
title_full Synthesis, characterization, applications, and challenges of iron oxide nanoparticles
title_fullStr Synthesis, characterization, applications, and challenges of iron oxide nanoparticles
title_full_unstemmed Synthesis, characterization, applications, and challenges of iron oxide nanoparticles
title_sort synthesis, characterization, applications, and challenges of iron oxide nanoparticles
publisher Dove Medical Press
publishDate 2016
url https://doaj.org/article/caaf9c49d0bf4a13932ddcbd4bb9fee5
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