Dual mechanism β-amino acid polymers promoting cell adhesion

Cell adhesion peptides like RGD are important to biomedical applications but suffer from proteolysis as well as processing and cost issues. Here, the authors report on the development of cationic-hydrophobic amphiphilic β-amino acid polymers which function as cell adhesion motifs but are resistant t...

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Autores principales:	Qi Chen, Donghui Zhang, Wenjing Zhang, Haodong Zhang, Jingcheng Zou, Mingjiao Chen, Jin Li, Yuan Yuan, Runhui Liu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/cabb85285ea448c782301257b7f93865
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id	oai:doaj.org-article:cabb85285ea448c782301257b7f93865
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spelling	oai:doaj.org-article:cabb85285ea448c782301257b7f938652021-12-02T13:57:44ZDual mechanism β-amino acid polymers promoting cell adhesion10.1038/s41467-020-20858-x2041-1723https://doaj.org/article/cabb85285ea448c782301257b7f938652021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20858-xhttps://doaj.org/toc/2041-1723Cell adhesion peptides like RGD are important to biomedical applications but suffer from proteolysis as well as processing and cost issues. Here, the authors report on the development of cationic-hydrophobic amphiphilic β-amino acid polymers which function as cell adhesion motifs but are resistant to proteolysis.Qi ChenDonghui ZhangWenjing ZhangHaodong ZhangJingcheng ZouMingjiao ChenJin LiYuan YuanRunhui LiuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Qi Chen Donghui Zhang Wenjing Zhang Haodong Zhang Jingcheng Zou Mingjiao Chen Jin Li Yuan Yuan Runhui Liu Dual mechanism β-amino acid polymers promoting cell adhesion
description	Cell adhesion peptides like RGD are important to biomedical applications but suffer from proteolysis as well as processing and cost issues. Here, the authors report on the development of cationic-hydrophobic amphiphilic β-amino acid polymers which function as cell adhesion motifs but are resistant to proteolysis.
format	article
author	Qi Chen Donghui Zhang Wenjing Zhang Haodong Zhang Jingcheng Zou Mingjiao Chen Jin Li Yuan Yuan Runhui Liu
author_facet	Qi Chen Donghui Zhang Wenjing Zhang Haodong Zhang Jingcheng Zou Mingjiao Chen Jin Li Yuan Yuan Runhui Liu
author_sort	Qi Chen
title	Dual mechanism β-amino acid polymers promoting cell adhesion
title_short	Dual mechanism β-amino acid polymers promoting cell adhesion
title_full	Dual mechanism β-amino acid polymers promoting cell adhesion
title_fullStr	Dual mechanism β-amino acid polymers promoting cell adhesion
title_full_unstemmed	Dual mechanism β-amino acid polymers promoting cell adhesion
title_sort	dual mechanism β-amino acid polymers promoting cell adhesion
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/cabb85285ea448c782301257b7f93865
work_keys_str_mv	AT qichen dualmechanismbaminoacidpolymerspromotingcelladhesion AT donghuizhang dualmechanismbaminoacidpolymerspromotingcelladhesion AT wenjingzhang dualmechanismbaminoacidpolymerspromotingcelladhesion AT haodongzhang dualmechanismbaminoacidpolymerspromotingcelladhesion AT jingchengzou dualmechanismbaminoacidpolymerspromotingcelladhesion AT mingjiaochen dualmechanismbaminoacidpolymerspromotingcelladhesion AT jinli dualmechanismbaminoacidpolymerspromotingcelladhesion AT yuanyuan dualmechanismbaminoacidpolymerspromotingcelladhesion AT runhuiliu dualmechanismbaminoacidpolymerspromotingcelladhesion
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Dual mechanism β-amino acid polymers promoting cell adhesion

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