Long‐term effects of obesity on COVID‐19 patients discharged from hospital
Abstract Introduction Obesity has been reported as a risk factor for COVID‐19 prognosis. However, the long‐term effects of obesity on patients discharged from the hospital are unclear, and the present study aims to address this issue. Methods A cohort study was conducted using data from patients dia...
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2021
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oai:doaj.org-article:cac068853cca49ff9d2e454ba3e6aa702021-11-12T19:57:15ZLong‐term effects of obesity on COVID‐19 patients discharged from hospital2050-452710.1002/iid3.522https://doaj.org/article/cac068853cca49ff9d2e454ba3e6aa702021-12-01T00:00:00Zhttps://doi.org/10.1002/iid3.522https://doaj.org/toc/2050-4527Abstract Introduction Obesity has been reported as a risk factor for COVID‐19 prognosis. However, the long‐term effects of obesity on patients discharged from the hospital are unclear, and the present study aims to address this issue. Methods A cohort study was conducted using data from patients diagnosed with COVID‐19 who were discharged from Wuhan Union Hospital between February 20, 2020, and March 20, 2020. The 118 patients with COVID‐19 were divided into the non‐obesity group and the obesity group according to their body mass index (BMI). All the patients were invited to fill out a series of scales to assess cardiopulmonary function. Data on population baseline characteristics, clinical manifestations, laboratory examinations, chest computed tomography (CT), and lung function were collected and analyzed. Results The clinical manifestations and pathological changes on CT images of obese patients were more serious after discharge than those of non‐obese patients. In addition, we found significant abnormalities in metabolic indicators such as blood lipids, uric acid, and liver function in obese patients. Most importantly, the antibody titer of COVID‐19 obese patients was inversely correlated with BMI. Conclusion In the long term, obesity affects clinical manifestations, immune function and endocrine metabolism in patients discharged after recovering from COVID‐19.Luorui ShangLi WangFangyuan ZhouJinxiao LiYuhan LiuShenglan YangWileyarticleantibody titerblood lipidbody mass indexCOVID‐19obesitySARS‐CoV‐2Immunologic diseases. AllergyRC581-607ENImmunity, Inflammation and Disease, Vol 9, Iss 4, Pp 1678-1685 (2021) |
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DOAJ |
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antibody titer blood lipid body mass index COVID‐19 obesity SARS‐CoV‐2 Immunologic diseases. Allergy RC581-607 |
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antibody titer blood lipid body mass index COVID‐19 obesity SARS‐CoV‐2 Immunologic diseases. Allergy RC581-607 Luorui Shang Li Wang Fangyuan Zhou Jinxiao Li Yuhan Liu Shenglan Yang Long‐term effects of obesity on COVID‐19 patients discharged from hospital |
| description |
Abstract Introduction Obesity has been reported as a risk factor for COVID‐19 prognosis. However, the long‐term effects of obesity on patients discharged from the hospital are unclear, and the present study aims to address this issue. Methods A cohort study was conducted using data from patients diagnosed with COVID‐19 who were discharged from Wuhan Union Hospital between February 20, 2020, and March 20, 2020. The 118 patients with COVID‐19 were divided into the non‐obesity group and the obesity group according to their body mass index (BMI). All the patients were invited to fill out a series of scales to assess cardiopulmonary function. Data on population baseline characteristics, clinical manifestations, laboratory examinations, chest computed tomography (CT), and lung function were collected and analyzed. Results The clinical manifestations and pathological changes on CT images of obese patients were more serious after discharge than those of non‐obese patients. In addition, we found significant abnormalities in metabolic indicators such as blood lipids, uric acid, and liver function in obese patients. Most importantly, the antibody titer of COVID‐19 obese patients was inversely correlated with BMI. Conclusion In the long term, obesity affects clinical manifestations, immune function and endocrine metabolism in patients discharged after recovering from COVID‐19. |
| format |
article |
| author |
Luorui Shang Li Wang Fangyuan Zhou Jinxiao Li Yuhan Liu Shenglan Yang |
| author_facet |
Luorui Shang Li Wang Fangyuan Zhou Jinxiao Li Yuhan Liu Shenglan Yang |
| author_sort |
Luorui Shang |
| title |
Long‐term effects of obesity on COVID‐19 patients discharged from hospital |
| title_short |
Long‐term effects of obesity on COVID‐19 patients discharged from hospital |
| title_full |
Long‐term effects of obesity on COVID‐19 patients discharged from hospital |
| title_fullStr |
Long‐term effects of obesity on COVID‐19 patients discharged from hospital |
| title_full_unstemmed |
Long‐term effects of obesity on COVID‐19 patients discharged from hospital |
| title_sort |
long‐term effects of obesity on covid‐19 patients discharged from hospital |
| publisher |
Wiley |
| publishDate |
2021 |
| url |
https://doaj.org/article/cac068853cca49ff9d2e454ba3e6aa70 |
| work_keys_str_mv |
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