Functional cardiac fibroblasts derived from human pluripotent stem cells via second heart field progenitors

Cardiac fibroblasts (CFs) play critical roles in heart development, homeostasis, and disease. Here the authors efficiently differentiate human pluripotent stem cells through second heart field progenitors to CFs that exhibit features and functional properties similar to native CFs.

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Detalles Bibliográficos
Autores principales:	Jianhua Zhang, Ran Tao, Katherine F. Campbell, Juliana L. Carvalho, Edward C. Ruiz, Gina C. Kim, Eric G. Schmuck, Amish N. Raval, André Monteiro da Rocha, Todd J. Herron, José Jalife, James A. Thomson, Timothy J. Kamp
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/cac0b63036aa4319872cc66f34cdaf9b
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spelling	oai:doaj.org-article:cac0b63036aa4319872cc66f34cdaf9b2021-12-02T16:57:32ZFunctional cardiac fibroblasts derived from human pluripotent stem cells via second heart field progenitors10.1038/s41467-019-09831-52041-1723https://doaj.org/article/cac0b63036aa4319872cc66f34cdaf9b2019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09831-5https://doaj.org/toc/2041-1723Cardiac fibroblasts (CFs) play critical roles in heart development, homeostasis, and disease. Here the authors efficiently differentiate human pluripotent stem cells through second heart field progenitors to CFs that exhibit features and functional properties similar to native CFs.Jianhua ZhangRan TaoKatherine F. CampbellJuliana L. CarvalhoEdward C. RuizGina C. KimEric G. SchmuckAmish N. RavalAndré Monteiro da RochaTodd J. HerronJosé JalifeJames A. ThomsonTimothy J. KampNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jianhua Zhang Ran Tao Katherine F. Campbell Juliana L. Carvalho Edward C. Ruiz Gina C. Kim Eric G. Schmuck Amish N. Raval André Monteiro da Rocha Todd J. Herron José Jalife James A. Thomson Timothy J. Kamp Functional cardiac fibroblasts derived from human pluripotent stem cells via second heart field progenitors
description	Cardiac fibroblasts (CFs) play critical roles in heart development, homeostasis, and disease. Here the authors efficiently differentiate human pluripotent stem cells through second heart field progenitors to CFs that exhibit features and functional properties similar to native CFs.
format	article
author	Jianhua Zhang Ran Tao Katherine F. Campbell Juliana L. Carvalho Edward C. Ruiz Gina C. Kim Eric G. Schmuck Amish N. Raval André Monteiro da Rocha Todd J. Herron José Jalife James A. Thomson Timothy J. Kamp
author_facet	Jianhua Zhang Ran Tao Katherine F. Campbell Juliana L. Carvalho Edward C. Ruiz Gina C. Kim Eric G. Schmuck Amish N. Raval André Monteiro da Rocha Todd J. Herron José Jalife James A. Thomson Timothy J. Kamp
author_sort	Jianhua Zhang
title	Functional cardiac fibroblasts derived from human pluripotent stem cells via second heart field progenitors
title_short	Functional cardiac fibroblasts derived from human pluripotent stem cells via second heart field progenitors
title_full	Functional cardiac fibroblasts derived from human pluripotent stem cells via second heart field progenitors
title_fullStr	Functional cardiac fibroblasts derived from human pluripotent stem cells via second heart field progenitors
title_full_unstemmed	Functional cardiac fibroblasts derived from human pluripotent stem cells via second heart field progenitors
title_sort	functional cardiac fibroblasts derived from human pluripotent stem cells via second heart field progenitors
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/cac0b63036aa4319872cc66f34cdaf9b
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Functional cardiac fibroblasts derived from human pluripotent stem cells via second heart field progenitors

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