Induction of paclitaxel resistance by ERα mediated prohibitin mitochondrial-nuclear shuttling.

Paclitaxel is a drug within one of the most promising classes of anticancer agents. Unfortunately, clinical success of this drug has been limited by the insurgence of cellular resistance. To address this, Paclitaxel resistance was modeled in an in vitro system using estrogen treated prostate cancer...

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Autores principales: Pei Dong, Lijuan Jiang, Jianye Liu, Zhiming Wu, Shengjie Guo, Ziling Zhang, Fangjian Zhou, Zhuowei Liu
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/cac872817d27418e84e1b78a2020dc89
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