Functional characterization of the meiosis-specific DNA double-strand break inducing factor SPO-11 from C. elegans

Functional characterization of the meiosis-specific DNA double-strand break inducing factor SPO-11 from C. elegans

Abstract The programmed induction of meiotic DNA double-strand breaks (DSBs) by the evolutionarily conserved SPO-11 protein, which is structurally related to archaeal Topo VIA topoisomerases, triggers meiotic recombination. Identification of several meiosis-specific factors that are required for SPO...

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Autores principales: Hsin-Yi Yeh, Sheng-Wei Lin, Yi-Chun Wu, Nei-Li Chan, Peter Chi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/cac9161265444b8b8f35082c0e583989
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