Enantioselective [3+3] atroposelective annulation catalyzed by N-heterocyclic carbenes

Axially chiral compounds are commonly found in nature. Here, the authors show the highly enantioselective construction of axially chiral biaryls via an N-heterocyclic carbenes-catalyzed [3+3] atroposelective annulation of ynals with cyclic 1,3-diones.

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Bibliographic Details
Main Authors: Changgui Zhao, Donghui Guo, Kristin Munkerup, Kuo-Wei Huang, Fangyi Li, Jian Wang
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/caca689026b84ad7bafd64c9ed7fd5d3
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