A cascade double 1,4-addition/intramolecular annulation strategy for expeditious assembly of unsymmetrical dibenzofurans

Existing routes to dibenzofurans have intrinsic regioselectivity, limiting the substitution patterns available in the products. Here a double 1,4-conjugate addition-annulation cascade between propargylamines and imidazolium methylides provides direct access to dibenzofurans with a complementary subs...

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Autores principales: Xinwei He, Ruxue Li, Pui Ying Choy, Mengqing Xie, Jiahui Duan, Qiang Tang, Yongjia Shang, Fuk Yee Kwong
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/cace364f9974467abb765d0621c9d0a3
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spelling oai:doaj.org-article:cace364f9974467abb765d0621c9d0a32021-12-02T13:24:05ZA cascade double 1,4-addition/intramolecular annulation strategy for expeditious assembly of unsymmetrical dibenzofurans10.1038/s42004-021-00478-22399-3669https://doaj.org/article/cace364f9974467abb765d0621c9d0a32021-03-01T00:00:00Zhttps://doi.org/10.1038/s42004-021-00478-2https://doaj.org/toc/2399-3669Existing routes to dibenzofurans have intrinsic regioselectivity, limiting the substitution patterns available in the products. Here a double 1,4-conjugate addition-annulation cascade between propargylamines and imidazolium methylides provides direct access to dibenzofurans with a complementary substitution pattern.Xinwei HeRuxue LiPui Ying ChoyMengqing XieJiahui DuanQiang TangYongjia ShangFuk Yee KwongNature PortfolioarticleChemistryQD1-999ENCommunications Chemistry, Vol 4, Iss 1, Pp 1-10 (2021)
institution DOAJ
collection DOAJ
language EN
topic Chemistry
QD1-999
spellingShingle Chemistry
QD1-999
Xinwei He
Ruxue Li
Pui Ying Choy
Mengqing Xie
Jiahui Duan
Qiang Tang
Yongjia Shang
Fuk Yee Kwong
A cascade double 1,4-addition/intramolecular annulation strategy for expeditious assembly of unsymmetrical dibenzofurans
description Existing routes to dibenzofurans have intrinsic regioselectivity, limiting the substitution patterns available in the products. Here a double 1,4-conjugate addition-annulation cascade between propargylamines and imidazolium methylides provides direct access to dibenzofurans with a complementary substitution pattern.
format article
author Xinwei He
Ruxue Li
Pui Ying Choy
Mengqing Xie
Jiahui Duan
Qiang Tang
Yongjia Shang
Fuk Yee Kwong
author_facet Xinwei He
Ruxue Li
Pui Ying Choy
Mengqing Xie
Jiahui Duan
Qiang Tang
Yongjia Shang
Fuk Yee Kwong
author_sort Xinwei He
title A cascade double 1,4-addition/intramolecular annulation strategy for expeditious assembly of unsymmetrical dibenzofurans
title_short A cascade double 1,4-addition/intramolecular annulation strategy for expeditious assembly of unsymmetrical dibenzofurans
title_full A cascade double 1,4-addition/intramolecular annulation strategy for expeditious assembly of unsymmetrical dibenzofurans
title_fullStr A cascade double 1,4-addition/intramolecular annulation strategy for expeditious assembly of unsymmetrical dibenzofurans
title_full_unstemmed A cascade double 1,4-addition/intramolecular annulation strategy for expeditious assembly of unsymmetrical dibenzofurans
title_sort cascade double 1,4-addition/intramolecular annulation strategy for expeditious assembly of unsymmetrical dibenzofurans
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/cace364f9974467abb765d0621c9d0a3
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