A cascade double 1,4-addition/intramolecular annulation strategy for expeditious assembly of unsymmetrical dibenzofurans
Existing routes to dibenzofurans have intrinsic regioselectivity, limiting the substitution patterns available in the products. Here a double 1,4-conjugate addition-annulation cascade between propargylamines and imidazolium methylides provides direct access to dibenzofurans with a complementary subs...
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Nature Portfolio
2021
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oai:doaj.org-article:cace364f9974467abb765d0621c9d0a32021-12-02T13:24:05ZA cascade double 1,4-addition/intramolecular annulation strategy for expeditious assembly of unsymmetrical dibenzofurans10.1038/s42004-021-00478-22399-3669https://doaj.org/article/cace364f9974467abb765d0621c9d0a32021-03-01T00:00:00Zhttps://doi.org/10.1038/s42004-021-00478-2https://doaj.org/toc/2399-3669Existing routes to dibenzofurans have intrinsic regioselectivity, limiting the substitution patterns available in the products. Here a double 1,4-conjugate addition-annulation cascade between propargylamines and imidazolium methylides provides direct access to dibenzofurans with a complementary substitution pattern.Xinwei HeRuxue LiPui Ying ChoyMengqing XieJiahui DuanQiang TangYongjia ShangFuk Yee KwongNature PortfolioarticleChemistryQD1-999ENCommunications Chemistry, Vol 4, Iss 1, Pp 1-10 (2021) |
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Chemistry QD1-999 |
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Chemistry QD1-999 Xinwei He Ruxue Li Pui Ying Choy Mengqing Xie Jiahui Duan Qiang Tang Yongjia Shang Fuk Yee Kwong A cascade double 1,4-addition/intramolecular annulation strategy for expeditious assembly of unsymmetrical dibenzofurans |
description |
Existing routes to dibenzofurans have intrinsic regioselectivity, limiting the substitution patterns available in the products. Here a double 1,4-conjugate addition-annulation cascade between propargylamines and imidazolium methylides provides direct access to dibenzofurans with a complementary substitution pattern. |
format |
article |
author |
Xinwei He Ruxue Li Pui Ying Choy Mengqing Xie Jiahui Duan Qiang Tang Yongjia Shang Fuk Yee Kwong |
author_facet |
Xinwei He Ruxue Li Pui Ying Choy Mengqing Xie Jiahui Duan Qiang Tang Yongjia Shang Fuk Yee Kwong |
author_sort |
Xinwei He |
title |
A cascade double 1,4-addition/intramolecular annulation strategy for expeditious assembly of unsymmetrical dibenzofurans |
title_short |
A cascade double 1,4-addition/intramolecular annulation strategy for expeditious assembly of unsymmetrical dibenzofurans |
title_full |
A cascade double 1,4-addition/intramolecular annulation strategy for expeditious assembly of unsymmetrical dibenzofurans |
title_fullStr |
A cascade double 1,4-addition/intramolecular annulation strategy for expeditious assembly of unsymmetrical dibenzofurans |
title_full_unstemmed |
A cascade double 1,4-addition/intramolecular annulation strategy for expeditious assembly of unsymmetrical dibenzofurans |
title_sort |
cascade double 1,4-addition/intramolecular annulation strategy for expeditious assembly of unsymmetrical dibenzofurans |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/cace364f9974467abb765d0621c9d0a3 |
work_keys_str_mv |
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