Repulsive cues combined with physical barriers and cell–cell adhesion determine progenitor cell positioning during organogenesis

The precise positioning of organ progenitor cells is essential for organ development and function. Here the authors use live imaging and mathematical modelling to show that the confinement of a motile progenitor cell population results from coupled physical barriers and cell-cell interactions.

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Autores principales: Azadeh Paksa, Jan Bandemer, Burkhard Hoeckendorf, Nitzan Razin, Katsiaryna Tarbashevich, Sofia Minina, Dana Meyen, Antonio Biundo, Sebastian A. Leidel, Nadine Peyrieras, Nir S. Gov, Philipp J. Keller, Erez Raz
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/cad910bf38ae49fd97e735fdb54507c4
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spelling oai:doaj.org-article:cad910bf38ae49fd97e735fdb54507c42021-12-02T15:34:31ZRepulsive cues combined with physical barriers and cell–cell adhesion determine progenitor cell positioning during organogenesis10.1038/ncomms112882041-1723https://doaj.org/article/cad910bf38ae49fd97e735fdb54507c42016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11288https://doaj.org/toc/2041-1723The precise positioning of organ progenitor cells is essential for organ development and function. Here the authors use live imaging and mathematical modelling to show that the confinement of a motile progenitor cell population results from coupled physical barriers and cell-cell interactions.Azadeh PaksaJan BandemerBurkhard HoeckendorfNitzan RazinKatsiaryna TarbashevichSofia MininaDana MeyenAntonio BiundoSebastian A. LeidelNadine PeyrierasNir S. GovPhilipp J. KellerErez RazNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Azadeh Paksa
Jan Bandemer
Burkhard Hoeckendorf
Nitzan Razin
Katsiaryna Tarbashevich
Sofia Minina
Dana Meyen
Antonio Biundo
Sebastian A. Leidel
Nadine Peyrieras
Nir S. Gov
Philipp J. Keller
Erez Raz
Repulsive cues combined with physical barriers and cell–cell adhesion determine progenitor cell positioning during organogenesis
description The precise positioning of organ progenitor cells is essential for organ development and function. Here the authors use live imaging and mathematical modelling to show that the confinement of a motile progenitor cell population results from coupled physical barriers and cell-cell interactions.
format article
author Azadeh Paksa
Jan Bandemer
Burkhard Hoeckendorf
Nitzan Razin
Katsiaryna Tarbashevich
Sofia Minina
Dana Meyen
Antonio Biundo
Sebastian A. Leidel
Nadine Peyrieras
Nir S. Gov
Philipp J. Keller
Erez Raz
author_facet Azadeh Paksa
Jan Bandemer
Burkhard Hoeckendorf
Nitzan Razin
Katsiaryna Tarbashevich
Sofia Minina
Dana Meyen
Antonio Biundo
Sebastian A. Leidel
Nadine Peyrieras
Nir S. Gov
Philipp J. Keller
Erez Raz
author_sort Azadeh Paksa
title Repulsive cues combined with physical barriers and cell–cell adhesion determine progenitor cell positioning during organogenesis
title_short Repulsive cues combined with physical barriers and cell–cell adhesion determine progenitor cell positioning during organogenesis
title_full Repulsive cues combined with physical barriers and cell–cell adhesion determine progenitor cell positioning during organogenesis
title_fullStr Repulsive cues combined with physical barriers and cell–cell adhesion determine progenitor cell positioning during organogenesis
title_full_unstemmed Repulsive cues combined with physical barriers and cell–cell adhesion determine progenitor cell positioning during organogenesis
title_sort repulsive cues combined with physical barriers and cell–cell adhesion determine progenitor cell positioning during organogenesis
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/cad910bf38ae49fd97e735fdb54507c4
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