Repulsive cues combined with physical barriers and cell–cell adhesion determine progenitor cell positioning during organogenesis
The precise positioning of organ progenitor cells is essential for organ development and function. Here the authors use live imaging and mathematical modelling to show that the confinement of a motile progenitor cell population results from coupled physical barriers and cell-cell interactions.
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Nature Portfolio
2016
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oai:doaj.org-article:cad910bf38ae49fd97e735fdb54507c42021-12-02T15:34:31ZRepulsive cues combined with physical barriers and cell–cell adhesion determine progenitor cell positioning during organogenesis10.1038/ncomms112882041-1723https://doaj.org/article/cad910bf38ae49fd97e735fdb54507c42016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11288https://doaj.org/toc/2041-1723The precise positioning of organ progenitor cells is essential for organ development and function. Here the authors use live imaging and mathematical modelling to show that the confinement of a motile progenitor cell population results from coupled physical barriers and cell-cell interactions.Azadeh PaksaJan BandemerBurkhard HoeckendorfNitzan RazinKatsiaryna TarbashevichSofia MininaDana MeyenAntonio BiundoSebastian A. LeidelNadine PeyrierasNir S. GovPhilipp J. KellerErez RazNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016) |
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Science Q Azadeh Paksa Jan Bandemer Burkhard Hoeckendorf Nitzan Razin Katsiaryna Tarbashevich Sofia Minina Dana Meyen Antonio Biundo Sebastian A. Leidel Nadine Peyrieras Nir S. Gov Philipp J. Keller Erez Raz Repulsive cues combined with physical barriers and cell–cell adhesion determine progenitor cell positioning during organogenesis |
description |
The precise positioning of organ progenitor cells is essential for organ development and function. Here the authors use live imaging and mathematical modelling to show that the confinement of a motile progenitor cell population results from coupled physical barriers and cell-cell interactions. |
format |
article |
author |
Azadeh Paksa Jan Bandemer Burkhard Hoeckendorf Nitzan Razin Katsiaryna Tarbashevich Sofia Minina Dana Meyen Antonio Biundo Sebastian A. Leidel Nadine Peyrieras Nir S. Gov Philipp J. Keller Erez Raz |
author_facet |
Azadeh Paksa Jan Bandemer Burkhard Hoeckendorf Nitzan Razin Katsiaryna Tarbashevich Sofia Minina Dana Meyen Antonio Biundo Sebastian A. Leidel Nadine Peyrieras Nir S. Gov Philipp J. Keller Erez Raz |
author_sort |
Azadeh Paksa |
title |
Repulsive cues combined with physical barriers and cell–cell adhesion determine progenitor cell positioning during organogenesis |
title_short |
Repulsive cues combined with physical barriers and cell–cell adhesion determine progenitor cell positioning during organogenesis |
title_full |
Repulsive cues combined with physical barriers and cell–cell adhesion determine progenitor cell positioning during organogenesis |
title_fullStr |
Repulsive cues combined with physical barriers and cell–cell adhesion determine progenitor cell positioning during organogenesis |
title_full_unstemmed |
Repulsive cues combined with physical barriers and cell–cell adhesion determine progenitor cell positioning during organogenesis |
title_sort |
repulsive cues combined with physical barriers and cell–cell adhesion determine progenitor cell positioning during organogenesis |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/cad910bf38ae49fd97e735fdb54507c4 |
work_keys_str_mv |
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