Knockdown of long noncoding RNA GAS5 reduces vascular smooth muscle cell apoptosis by inactivating EZH2-mediated RIG-I signaling pathway in abdominal aortic aneurysm

Knockdown of long noncoding RNA GAS5 reduces vascular smooth muscle cell apoptosis by inactivating EZH2-mediated RIG-I signaling pathway in abdominal aortic aneurysm

Abstract Background Abdominal aortic aneurysm (AAA), an irreversible cardiovascular disease prevalent in the artery, causes the increase of the aneurysm diameter over time, and is a fatal phenomenon inducing sidewall rupture. Long noncoding RNAs (lncRNAs) serve as promising biomarkers for AAA. In th...

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Autores principales: Tianming Le, Xin He, Jianhua Huang, Shuai Liu, Yang Bai, Kemin Wu
Formato: article
Lenguaje:EN
Publicado: BMC 2021
Materias:
Abdominal aortic aneurysm
Smooth muscle cells
Apoptosis
GAS5
EZH2
RIG-I
Medicine
R
Acceso en línea:https://doaj.org/article/cae899a122744dfda01c458551a69652
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