Negative auto-regulation of myostatin expression is mediated by Smad3 and microRNA-27.

Negative auto-regulation of myostatin expression is mediated by Smad3 and microRNA-27.

Growth factors, such as myostatin (Mstn), play an important role in regulating post-natal myogenesis. In fact, loss of Mstn has been shown to result in increased post-natal muscle growth through enhanced satellite cell functionality; while elevated levels of Mstn result in dramatic skeletal muscle w...

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Autores principales: Craig McFarlane, Anuradha Vajjala, Harikumar Arigela, Sudarsanareddy Lokireddy, XiaoJia Ge, Sabeera Bonala, Ravikumar Manickam, Ravi Kambadur, Mridula Sharma
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/caed4fe2d0964f6892cbaf516797836f
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