The conformational wave in capsaicin activation of transient receptor potential vanilloid 1 ion channel
The capsaicin receptor TRPV1 has been structurally characterized, but the capsaicin activation dynamics remain elusive. Here authors use fluorescent unnatural amino acid incorporation, computational modeling and Φ-analysis to derive the capsaicin-bound open state model and reveal the capsaicin induc...
Enregistré dans:
| Auteurs principaux: | , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2018
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/caedacb6329047018a4de94230ee9e09 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|