Using regulatory variants to detect gene–gene interactions identifies networks of genes linked to cell immortalisation

For most human genes nearby regulatory variants explain only a small proportion of their expression variation between individuals. Here the authors show how the impact of a gene’s set of nearby regulatory variant is often linked to the expression levels of distal genes, providing insights into gene...

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Bibliographic Details
Main Authors: D. Wragg, Q. Liu, Z. Lin, V. Riggio, C. A. Pugh, A. J. Beveridge, H. Brown, D. A. Hume, S. E. Harris, I. J. Deary, A. Tenesa, J. G. D. Prendergast
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/caf3c6c3130d4e6b811575159199dd1a
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