Classification of skin phenotypes caused by diabetes mellitus using complex scattering parameters in the millimeter-wave frequency range

Abstract The pathological skin phenotype caused by hyperglycemia is an important indicator for the progress of diabetes mellitus. An early detection of diabetes assures an early intervention to regulate the carbohydrate metabolism. In this publication a non-invasive detection principle based on the...

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Autores principales: Fabian Dornuf, Pedro Martín-Mateos, Blanca Duarte, Bernhard Hils, Oscar Elias Bonilla-Manrique, Fernando Larcher, Pablo Acedo, Viktor Krozer
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Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/cafac1b43c9943918457cbca25b69662
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spelling oai:doaj.org-article:cafac1b43c9943918457cbca25b696622021-12-02T11:40:34ZClassification of skin phenotypes caused by diabetes mellitus using complex scattering parameters in the millimeter-wave frequency range10.1038/s41598-017-06034-02045-2322https://doaj.org/article/cafac1b43c9943918457cbca25b696622017-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-06034-0https://doaj.org/toc/2045-2322Abstract The pathological skin phenotype caused by hyperglycemia is an important indicator for the progress of diabetes mellitus. An early detection of diabetes assures an early intervention to regulate the carbohydrate metabolism. In this publication a non-invasive detection principle based on the measurement of complex scattering parameters in the millimeter-wave frequency range is presented. The measurement principle provides evidence of the applicability for the identification of different glycemic states in animal models. The method proposed here can be used to predict diabetes status in animal models and is interesting for application on humans in view of safeness of millimeter-wave radiation. Furthermore the complex scattering parameters give important information about the anatomic varieties between the analyzed skin samples of the different mice strains. In contrast to other methods, our approach is less sensitive to skin variations between animals.Fabian DornufPedro Martín-MateosBlanca DuarteBernhard HilsOscar Elias Bonilla-ManriqueFernando LarcherPablo AcedoViktor KrozerNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Fabian Dornuf
Pedro Martín-Mateos
Blanca Duarte
Bernhard Hils
Oscar Elias Bonilla-Manrique
Fernando Larcher
Pablo Acedo
Viktor Krozer
Classification of skin phenotypes caused by diabetes mellitus using complex scattering parameters in the millimeter-wave frequency range
description Abstract The pathological skin phenotype caused by hyperglycemia is an important indicator for the progress of diabetes mellitus. An early detection of diabetes assures an early intervention to regulate the carbohydrate metabolism. In this publication a non-invasive detection principle based on the measurement of complex scattering parameters in the millimeter-wave frequency range is presented. The measurement principle provides evidence of the applicability for the identification of different glycemic states in animal models. The method proposed here can be used to predict diabetes status in animal models and is interesting for application on humans in view of safeness of millimeter-wave radiation. Furthermore the complex scattering parameters give important information about the anatomic varieties between the analyzed skin samples of the different mice strains. In contrast to other methods, our approach is less sensitive to skin variations between animals.
format article
author Fabian Dornuf
Pedro Martín-Mateos
Blanca Duarte
Bernhard Hils
Oscar Elias Bonilla-Manrique
Fernando Larcher
Pablo Acedo
Viktor Krozer
author_facet Fabian Dornuf
Pedro Martín-Mateos
Blanca Duarte
Bernhard Hils
Oscar Elias Bonilla-Manrique
Fernando Larcher
Pablo Acedo
Viktor Krozer
author_sort Fabian Dornuf
title Classification of skin phenotypes caused by diabetes mellitus using complex scattering parameters in the millimeter-wave frequency range
title_short Classification of skin phenotypes caused by diabetes mellitus using complex scattering parameters in the millimeter-wave frequency range
title_full Classification of skin phenotypes caused by diabetes mellitus using complex scattering parameters in the millimeter-wave frequency range
title_fullStr Classification of skin phenotypes caused by diabetes mellitus using complex scattering parameters in the millimeter-wave frequency range
title_full_unstemmed Classification of skin phenotypes caused by diabetes mellitus using complex scattering parameters in the millimeter-wave frequency range
title_sort classification of skin phenotypes caused by diabetes mellitus using complex scattering parameters in the millimeter-wave frequency range
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/cafac1b43c9943918457cbca25b69662
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AT blancaduarte classificationofskinphenotypescausedbydiabetesmellitususingcomplexscatteringparametersinthemillimeterwavefrequencyrange
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