Cdt1 stabilizes an open MCM ring for helicase loading
The loading and activation of the Mcm2-7 replicative helicase couples cell cycle progression to DNA replication. Here the authors use X-ray crystallography and single-particle electron microscopy to demonstrate how Ctd1 functions to promote MCM loading onto DNA.
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2017
|
| Subjects: | |
| Online Access: | https://doaj.org/article/cb03dbf473dc4d6197f8ab99b9768f4a |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|