High throughput determination of TGFβ1/SMAD3 targets in A549 lung epithelial cells.

High throughput determination of TGFβ1/SMAD3 targets in A549 lung epithelial cells.

<h4>Background</h4>Transforming growth factor beta 1 (TGFβ1) plays a major role in many lung diseases including lung cancer, pulmonary hypertension, and pulmonary fibrosis. TGFβ1 activates a signal transduction cascade that results in the transcriptional regulation of genes in the nucleu...

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Autores principales: Yingze Zhang, Daniel Handley, Tommy Kaplan, Haiying Yu, Abha S Bais, Thomas Richards, Kusum V Pandit, Qilu Zeng, Panayiotis V Benos, Nir Friedman, Oliver Eickelberg, Naftali Kaminski
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/cb04f5dd35134565991379b1fd3d92e8
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