Complete diastereodivergence in asymmetric 1,6-addition reactions enabled by minimal modification of a chiral catalyst

For reactions producing numerous chiral centres, accessing all potential stereoisomers is synthetically appealing but difficult. Here, the authors report a stereodivergent 1,6-addition of azlactones where minimal changes to the catalyst structure switches the product selectivity.

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Autores principales: Daisuke Uraguchi, Ken Yoshioka, Takashi Ooi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/cb122de58d3145f9950a5515d20f47b6
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