Complete diastereodivergence in asymmetric 1,6-addition reactions enabled by minimal modification of a chiral catalyst
For reactions producing numerous chiral centres, accessing all potential stereoisomers is synthetically appealing but difficult. Here, the authors report a stereodivergent 1,6-addition of azlactones where minimal changes to the catalyst structure switches the product selectivity.
Guardado en:
Autores principales: | Daisuke Uraguchi, Ken Yoshioka, Takashi Ooi |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/cb122de58d3145f9950a5515d20f47b6 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Asymmetric C(sp3)–H functionalization of unactivated alkylarenes such as toluene enabled by chiral Brønsted base catalysts
por: Tsubasa Hirata, et al.
Publicado: (2021) -
Enantiodivergence by minimal modification of an acyclic chiral secondary aminocatalyst
por: Jun Dai, et al.
Publicado: (2019) -
Helical Polycarbenes Bearing <i>D</i>-Prolinol Ester Pendants: An Efficient Catalyst for Asymmetric Michael Addition Reaction
por: Na Liu, et al.
Publicado: (2021) -
Improvement in aqueous solubility of achiral symmetric cyclofenil by modification to a chiral asymmetric analog
por: Junki Morimoto, et al.
Publicado: (2021) -
Divergent synthesis of chiral cyclic azides via asymmetric cycloaddition reactions of vinyl azides
por: Nuligonda Thirupathi, et al.
Publicado: (2019)