Extensive 5′-surveillance guards against non-canonical NAD-caps of nuclear mRNAs in yeast

NAD (nicotinamide adenine dinucleotide) acts as a non-canonical RNA cap structure in bacteria and eukaryotes. Here the authors demonstrate the whole landscape of budding yeast NAD-RNAs which are subject to diverse surveillance pathways, suggesting that NAD caps in budding yeast are mostly dysfunctio...

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Autores principales: Yaqing Zhang, David Kuster, Tobias Schmidt, Daniel Kirrmaier, Gabriele Nübel, David Ibberson, Vladimir Benes, Hans Hombauer, Michael Knop, Andres Jäschke
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/cb1a8be4555f41cba2402ba4c1a9d430
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spelling oai:doaj.org-article:cb1a8be4555f41cba2402ba4c1a9d4302021-12-02T15:39:07ZExtensive 5′-surveillance guards against non-canonical NAD-caps of nuclear mRNAs in yeast10.1038/s41467-020-19326-32041-1723https://doaj.org/article/cb1a8be4555f41cba2402ba4c1a9d4302020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19326-3https://doaj.org/toc/2041-1723NAD (nicotinamide adenine dinucleotide) acts as a non-canonical RNA cap structure in bacteria and eukaryotes. Here the authors demonstrate the whole landscape of budding yeast NAD-RNAs which are subject to diverse surveillance pathways, suggesting that NAD caps in budding yeast are mostly dysfunctional.Yaqing ZhangDavid KusterTobias SchmidtDaniel KirrmaierGabriele NübelDavid IbbersonVladimir BenesHans HombauerMichael KnopAndres JäschkeNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yaqing Zhang
David Kuster
Tobias Schmidt
Daniel Kirrmaier
Gabriele Nübel
David Ibberson
Vladimir Benes
Hans Hombauer
Michael Knop
Andres Jäschke
Extensive 5′-surveillance guards against non-canonical NAD-caps of nuclear mRNAs in yeast
description NAD (nicotinamide adenine dinucleotide) acts as a non-canonical RNA cap structure in bacteria and eukaryotes. Here the authors demonstrate the whole landscape of budding yeast NAD-RNAs which are subject to diverse surveillance pathways, suggesting that NAD caps in budding yeast are mostly dysfunctional.
format article
author Yaqing Zhang
David Kuster
Tobias Schmidt
Daniel Kirrmaier
Gabriele Nübel
David Ibberson
Vladimir Benes
Hans Hombauer
Michael Knop
Andres Jäschke
author_facet Yaqing Zhang
David Kuster
Tobias Schmidt
Daniel Kirrmaier
Gabriele Nübel
David Ibberson
Vladimir Benes
Hans Hombauer
Michael Knop
Andres Jäschke
author_sort Yaqing Zhang
title Extensive 5′-surveillance guards against non-canonical NAD-caps of nuclear mRNAs in yeast
title_short Extensive 5′-surveillance guards against non-canonical NAD-caps of nuclear mRNAs in yeast
title_full Extensive 5′-surveillance guards against non-canonical NAD-caps of nuclear mRNAs in yeast
title_fullStr Extensive 5′-surveillance guards against non-canonical NAD-caps of nuclear mRNAs in yeast
title_full_unstemmed Extensive 5′-surveillance guards against non-canonical NAD-caps of nuclear mRNAs in yeast
title_sort extensive 5′-surveillance guards against non-canonical nad-caps of nuclear mrnas in yeast
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/cb1a8be4555f41cba2402ba4c1a9d430
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