Precise through-space control of an abiotic electrophilic aromatic substitution reaction
Regioselectivity during electrophilic aromatic substitution is typically controlled by substituents on the aryl group. Here the authors report an electrophilic aromatic substitution reaction, wherein remote chiral ester groups direct the electrophile to a precise location on the molecule.
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Nature Portfolio
2017
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oai:doaj.org-article:cb1c33951f5949f3945f2056f03c82082021-12-02T14:42:55ZPrecise through-space control of an abiotic electrophilic aromatic substitution reaction10.1038/ncomms148402041-1723https://doaj.org/article/cb1c33951f5949f3945f2056f03c82082017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms14840https://doaj.org/toc/2041-1723Regioselectivity during electrophilic aromatic substitution is typically controlled by substituents on the aryl group. Here the authors report an electrophilic aromatic substitution reaction, wherein remote chiral ester groups direct the electrophile to a precise location on the molecule.Kyle E. MurphyJessica L. BocanegraXiaoxi LiuH.-Y. Katharine ChauPatrick C. LeeJianing LiSeverin T. SchneebeliNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-7 (2017) |
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Science Q Kyle E. Murphy Jessica L. Bocanegra Xiaoxi Liu H.-Y. Katharine Chau Patrick C. Lee Jianing Li Severin T. Schneebeli Precise through-space control of an abiotic electrophilic aromatic substitution reaction |
description |
Regioselectivity during electrophilic aromatic substitution is typically controlled by substituents on the aryl group. Here the authors report an electrophilic aromatic substitution reaction, wherein remote chiral ester groups direct the electrophile to a precise location on the molecule. |
format |
article |
author |
Kyle E. Murphy Jessica L. Bocanegra Xiaoxi Liu H.-Y. Katharine Chau Patrick C. Lee Jianing Li Severin T. Schneebeli |
author_facet |
Kyle E. Murphy Jessica L. Bocanegra Xiaoxi Liu H.-Y. Katharine Chau Patrick C. Lee Jianing Li Severin T. Schneebeli |
author_sort |
Kyle E. Murphy |
title |
Precise through-space control of an abiotic electrophilic aromatic substitution reaction |
title_short |
Precise through-space control of an abiotic electrophilic aromatic substitution reaction |
title_full |
Precise through-space control of an abiotic electrophilic aromatic substitution reaction |
title_fullStr |
Precise through-space control of an abiotic electrophilic aromatic substitution reaction |
title_full_unstemmed |
Precise through-space control of an abiotic electrophilic aromatic substitution reaction |
title_sort |
precise through-space control of an abiotic electrophilic aromatic substitution reaction |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/cb1c33951f5949f3945f2056f03c8208 |
work_keys_str_mv |
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