Precise through-space control of an abiotic electrophilic aromatic substitution reaction

Regioselectivity during electrophilic aromatic substitution is typically controlled by substituents on the aryl group. Here the authors report an electrophilic aromatic substitution reaction, wherein remote chiral ester groups direct the electrophile to a precise location on the molecule.

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Main Authors:	Kyle E. Murphy, Jessica L. Bocanegra, Xiaoxi Liu, H.-Y. Katharine Chau, Patrick C. Lee, Jianing Li, Severin T. Schneebeli
Format:	article
Language:	EN
Published:	Nature Portfolio 2017
Subjects:	Science Q
Online Access:	https://doaj.org/article/cb1c33951f5949f3945f2056f03c8208
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spelling	oai:doaj.org-article:cb1c33951f5949f3945f2056f03c82082021-12-02T14:42:55ZPrecise through-space control of an abiotic electrophilic aromatic substitution reaction10.1038/ncomms148402041-1723https://doaj.org/article/cb1c33951f5949f3945f2056f03c82082017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms14840https://doaj.org/toc/2041-1723Regioselectivity during electrophilic aromatic substitution is typically controlled by substituents on the aryl group. Here the authors report an electrophilic aromatic substitution reaction, wherein remote chiral ester groups direct the electrophile to a precise location on the molecule.Kyle E. MurphyJessica L. BocanegraXiaoxi LiuH.-Y. Katharine ChauPatrick C. LeeJianing LiSeverin T. SchneebeliNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kyle E. Murphy Jessica L. Bocanegra Xiaoxi Liu H.-Y. Katharine Chau Patrick C. Lee Jianing Li Severin T. Schneebeli Precise through-space control of an abiotic electrophilic aromatic substitution reaction
description	Regioselectivity during electrophilic aromatic substitution is typically controlled by substituents on the aryl group. Here the authors report an electrophilic aromatic substitution reaction, wherein remote chiral ester groups direct the electrophile to a precise location on the molecule.
format	article
author	Kyle E. Murphy Jessica L. Bocanegra Xiaoxi Liu H.-Y. Katharine Chau Patrick C. Lee Jianing Li Severin T. Schneebeli
author_facet	Kyle E. Murphy Jessica L. Bocanegra Xiaoxi Liu H.-Y. Katharine Chau Patrick C. Lee Jianing Li Severin T. Schneebeli
author_sort	Kyle E. Murphy
title	Precise through-space control of an abiotic electrophilic aromatic substitution reaction
title_short	Precise through-space control of an abiotic electrophilic aromatic substitution reaction
title_full	Precise through-space control of an abiotic electrophilic aromatic substitution reaction
title_fullStr	Precise through-space control of an abiotic electrophilic aromatic substitution reaction
title_full_unstemmed	Precise through-space control of an abiotic electrophilic aromatic substitution reaction
title_sort	precise through-space control of an abiotic electrophilic aromatic substitution reaction
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/cb1c33951f5949f3945f2056f03c8208
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Precise through-space control of an abiotic electrophilic aromatic substitution reaction

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