Precise through-space control of an abiotic electrophilic aromatic substitution reaction

Regioselectivity during electrophilic aromatic substitution is typically controlled by substituents on the aryl group. Here the authors report an electrophilic aromatic substitution reaction, wherein remote chiral ester groups direct the electrophile to a precise location on the molecule.

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Autores principales: Kyle E. Murphy, Jessica L. Bocanegra, Xiaoxi Liu, H.-Y. Katharine Chau, Patrick C. Lee, Jianing Li, Severin T. Schneebeli
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/cb1c33951f5949f3945f2056f03c8208
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spelling oai:doaj.org-article:cb1c33951f5949f3945f2056f03c82082021-12-02T14:42:55ZPrecise through-space control of an abiotic electrophilic aromatic substitution reaction10.1038/ncomms148402041-1723https://doaj.org/article/cb1c33951f5949f3945f2056f03c82082017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms14840https://doaj.org/toc/2041-1723Regioselectivity during electrophilic aromatic substitution is typically controlled by substituents on the aryl group. Here the authors report an electrophilic aromatic substitution reaction, wherein remote chiral ester groups direct the electrophile to a precise location on the molecule.Kyle E. MurphyJessica L. BocanegraXiaoxi LiuH.-Y. Katharine ChauPatrick C. LeeJianing LiSeverin T. SchneebeliNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kyle E. Murphy
Jessica L. Bocanegra
Xiaoxi Liu
H.-Y. Katharine Chau
Patrick C. Lee
Jianing Li
Severin T. Schneebeli
Precise through-space control of an abiotic electrophilic aromatic substitution reaction
description Regioselectivity during electrophilic aromatic substitution is typically controlled by substituents on the aryl group. Here the authors report an electrophilic aromatic substitution reaction, wherein remote chiral ester groups direct the electrophile to a precise location on the molecule.
format article
author Kyle E. Murphy
Jessica L. Bocanegra
Xiaoxi Liu
H.-Y. Katharine Chau
Patrick C. Lee
Jianing Li
Severin T. Schneebeli
author_facet Kyle E. Murphy
Jessica L. Bocanegra
Xiaoxi Liu
H.-Y. Katharine Chau
Patrick C. Lee
Jianing Li
Severin T. Schneebeli
author_sort Kyle E. Murphy
title Precise through-space control of an abiotic electrophilic aromatic substitution reaction
title_short Precise through-space control of an abiotic electrophilic aromatic substitution reaction
title_full Precise through-space control of an abiotic electrophilic aromatic substitution reaction
title_fullStr Precise through-space control of an abiotic electrophilic aromatic substitution reaction
title_full_unstemmed Precise through-space control of an abiotic electrophilic aromatic substitution reaction
title_sort precise through-space control of an abiotic electrophilic aromatic substitution reaction
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/cb1c33951f5949f3945f2056f03c8208
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