Backbone-independent NMR resonance assignments of methyl probes in large proteins

Here, the authors present Methyl Assignments Using Satisfiability (MAUS), a method for the assignment of methyl groups using raw NOE data. They use eight proteins in the 10–45 kDa size range as test cases and show that MAUS yields 100% accurate assignments at high completeness levels.

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Autores principales:	Santrupti Nerli, Viviane S. De Paula, Andrew C. McShan, Nikolaos G. Sgourakis
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/cb22eaddf85f4c9698cd9093fadb2f6b
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spelling	oai:doaj.org-article:cb22eaddf85f4c9698cd9093fadb2f6b2021-12-02T13:24:04ZBackbone-independent NMR resonance assignments of methyl probes in large proteins10.1038/s41467-021-20984-02041-1723https://doaj.org/article/cb22eaddf85f4c9698cd9093fadb2f6b2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-20984-0https://doaj.org/toc/2041-1723Here, the authors present Methyl Assignments Using Satisfiability (MAUS), a method for the assignment of methyl groups using raw NOE data. They use eight proteins in the 10–45 kDa size range as test cases and show that MAUS yields 100% accurate assignments at high completeness levels.Santrupti NerliViviane S. De PaulaAndrew C. McShanNikolaos G. SgourakisNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Santrupti Nerli Viviane S. De Paula Andrew C. McShan Nikolaos G. Sgourakis Backbone-independent NMR resonance assignments of methyl probes in large proteins
description	Here, the authors present Methyl Assignments Using Satisfiability (MAUS), a method for the assignment of methyl groups using raw NOE data. They use eight proteins in the 10–45 kDa size range as test cases and show that MAUS yields 100% accurate assignments at high completeness levels.
format	article
author	Santrupti Nerli Viviane S. De Paula Andrew C. McShan Nikolaos G. Sgourakis
author_facet	Santrupti Nerli Viviane S. De Paula Andrew C. McShan Nikolaos G. Sgourakis
author_sort	Santrupti Nerli
title	Backbone-independent NMR resonance assignments of methyl probes in large proteins
title_short	Backbone-independent NMR resonance assignments of methyl probes in large proteins
title_full	Backbone-independent NMR resonance assignments of methyl probes in large proteins
title_fullStr	Backbone-independent NMR resonance assignments of methyl probes in large proteins
title_full_unstemmed	Backbone-independent NMR resonance assignments of methyl probes in large proteins
title_sort	backbone-independent nmr resonance assignments of methyl probes in large proteins
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/cb22eaddf85f4c9698cd9093fadb2f6b
work_keys_str_mv	AT santruptinerli backboneindependentnmrresonanceassignmentsofmethylprobesinlargeproteins AT vivianesdepaula backboneindependentnmrresonanceassignmentsofmethylprobesinlargeproteins AT andrewcmcshan backboneindependentnmrresonanceassignmentsofmethylprobesinlargeproteins AT nikolaosgsgourakis backboneindependentnmrresonanceassignmentsofmethylprobesinlargeproteins
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Backbone-independent NMR resonance assignments of methyl probes in large proteins

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