Backbone-independent NMR resonance assignments of methyl probes in large proteins

Backbone-independent NMR resonance assignments of methyl probes in large proteins

Here, the authors present Methyl Assignments Using Satisfiability (MAUS), a method for the assignment of methyl groups using raw NOE data. They use eight proteins in the 10–45 kDa size range as test cases and show that MAUS yields 100% accurate assignments at high completeness levels.

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Autores principales: Santrupti Nerli, Viviane S. De Paula, Andrew C. McShan, Nikolaos G. Sgourakis
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
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Acceso en línea:https://doaj.org/article/cb22eaddf85f4c9698cd9093fadb2f6b
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