Single molecule analysis reveals monomeric XPA bends DNA and undergoes episodic linear diffusion during damage search
It is not fully understood how XPA interacts with a DNA lesion during nucleotide excision repair. Here, the authors use single molecule analysis to study XPA–DNA interactions, including the DNA bend angle, protein stoichiometry, and diffusive properties during damage search.
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Auteurs principaux: | , , , , , , , , , , |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2020
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Accès en ligne: | https://doaj.org/article/cb2429af2c074e93843b6cd1c155ebba |
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