Antagonistic Pleiotropy in the Bifunctional Surface Protein FadL (OmpP1) during Adaptation of <named-content content-type="genus-species">Haemophilus influenzae</named-content> to Chronic Lung Infection Associated with Chronic Obstructive Pulmonary Disease

ABSTRACT Tracking bacterial evolution during chronic infection provides insights into how host selection pressures shape bacterial genomes. The human-restricted opportunistic pathogen nontypeable Haemophilus influenzae (NTHi) infects the lower airways of patients suffering chronic obstructive pulmon...

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Autores principales:	Javier Moleres, Ariadna Fernández-Calvet, Rachel L. Ehrlich, Sara Martí, Lucía Pérez-Regidor, Begoña Euba, Irene Rodríguez-Arce, Sergey Balashov, Ester Cuevas, Josefina Liñares, Carmen Ardanuy, Sonsoles Martín-Santamaría, Garth D. Ehrlich, Joshua Chang Mell, Junkal Garmendia
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2018
Materias:	CEACAM1 FadL/OmpP1 Haemophilus influenzae adaptive evolution antagonistic pleiotropic chronic obstructive pulmonary disease Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/cb2d1564d60c4e4f982642d3ba3cf375
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Antagonistic Pleiotropy in the Bifunctional Surface Protein FadL (OmpP1) during Adaptation of <named-content content-type="genus-species">Haemophilus influenzae</named-content> to Chronic Lung Infection Associated with Chronic Obstructive Pulmonary Disease

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