A new stochastic model for subgenomic hepatitis C virus replication considers drug resistant mutants.

A new stochastic model for subgenomic hepatitis C virus replication considers drug resistant mutants.

As an RNA virus, hepatitis C virus (HCV) is able to rapidly acquire drug resistance, and for this reason the design of effective anti-HCV drugs is a real challenge. The HCV subgenomic replicon-containing cells are widely used for experimental studies of the HCV genome replication mechanisms, for dru...

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Autores principales: Nikita V Ivanisenko, Elena L Mishchenko, Ilya R Akberdin, Pavel S Demenkov, Vitaly A Likhoshvai, Konstantin N Kozlov, Dmitry I Todorov, Vitaly V Gursky, Maria G Samsonova, Alexander M Samsonov, Diana Clausznitzer, Lars Kaderali, Nikolay A Kolchanov, Vladimir A Ivanisenko
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/cb38672ba80c44689a4dc650e1639ee7
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