A new stochastic model for subgenomic hepatitis C virus replication considers drug resistant mutants.
As an RNA virus, hepatitis C virus (HCV) is able to rapidly acquire drug resistance, and for this reason the design of effective anti-HCV drugs is a real challenge. The HCV subgenomic replicon-containing cells are widely used for experimental studies of the HCV genome replication mechanisms, for dru...
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Main Authors: | , , , , , , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2014
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Subjects: | |
Online Access: | https://doaj.org/article/cb38672ba80c44689a4dc650e1639ee7 |
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