Placental Alkaline Phosphatase Promotes Zika Virus Replication by Stabilizing Viral Proteins through BIP

ABSTRACT Zika virus (ZIKV) infection during pregnancy causes intrauterine growth defects and microcephaly, but knowledge of the mechanism through which ZIKV infects and replicates in the placenta remains elusive. Here, we found that ALPP, an alkaline phosphatase expressed primarily in placental tiss...

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Bibliographic Details
Main Authors: Jian Chen, Zhilu Chen, Mingbin Liu, Tianyi Qiu, Daobin Feng, Chen Zhao, Shuye Zhang, Xiaoyan Zhang, Jianqing Xu
Format: article
Language:EN
Published: American Society for Microbiology 2020
Subjects:
BIP
Online Access:https://doaj.org/article/cb390dce90b1421a9e50dfc2071cf9b1
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