The prepulse inhibition deficit appearance is largely independent on the circadian cycle, body weight, and the gender of vasopressin deficient Brattleboro rat

Objective. A disturbance of sensorimotor gating measured by prepulse inhibition of acoustic startle (PPI) is one of the best tests of the schizophrenia-like behavior. Vasopressin was implicated in the development of schizophrenia; therefore, the naturally occurring vasopressin-deficient Brattleboro...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Fodor A, Klausz B, Toth B, Zelena D
Formato: article
Lenguaje:EN
Publicado: Sciendo 2016
Materias:
Acceso en línea:https://doaj.org/article/cb4277cd94f44a72a79a12dfd63baa48
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:cb4277cd94f44a72a79a12dfd63baa48
record_format dspace
spelling oai:doaj.org-article:cb4277cd94f44a72a79a12dfd63baa482021-12-02T15:29:49ZThe prepulse inhibition deficit appearance is largely independent on the circadian cycle, body weight, and the gender of vasopressin deficient Brattleboro rat1336-032910.1515/enr-2016-0004https://doaj.org/article/cb4277cd94f44a72a79a12dfd63baa482016-01-01T00:00:00Zhttps://doi.org/10.1515/enr-2016-0004https://doaj.org/toc/1336-0329Objective. A disturbance of sensorimotor gating measured by prepulse inhibition of acoustic startle (PPI) is one of the best tests of the schizophrenia-like behavior. Vasopressin was implicated in the development of schizophrenia; therefore, the naturally occurring vasopressin-deficient Brattleboro rat has been suggested to be a reliable non-pharmacological animal model. However, previous studies focusing on PPI deficit did not use proper control and despite clear gender differences in the development of the disorder, the effect of gender has been mostly neglected.Fodor AKlausz BToth BZelena DSciendoarticleschizophreniaketaminemalefemalelactationacoustic startle responseDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 50, Iss 1, Pp 16-23 (2016)
institution DOAJ
collection DOAJ
language EN
topic schizophrenia
ketamine
male
female
lactation
acoustic startle response
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
spellingShingle schizophrenia
ketamine
male
female
lactation
acoustic startle response
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
Fodor A
Klausz B
Toth B
Zelena D
The prepulse inhibition deficit appearance is largely independent on the circadian cycle, body weight, and the gender of vasopressin deficient Brattleboro rat
description Objective. A disturbance of sensorimotor gating measured by prepulse inhibition of acoustic startle (PPI) is one of the best tests of the schizophrenia-like behavior. Vasopressin was implicated in the development of schizophrenia; therefore, the naturally occurring vasopressin-deficient Brattleboro rat has been suggested to be a reliable non-pharmacological animal model. However, previous studies focusing on PPI deficit did not use proper control and despite clear gender differences in the development of the disorder, the effect of gender has been mostly neglected.
format article
author Fodor A
Klausz B
Toth B
Zelena D
author_facet Fodor A
Klausz B
Toth B
Zelena D
author_sort Fodor A
title The prepulse inhibition deficit appearance is largely independent on the circadian cycle, body weight, and the gender of vasopressin deficient Brattleboro rat
title_short The prepulse inhibition deficit appearance is largely independent on the circadian cycle, body weight, and the gender of vasopressin deficient Brattleboro rat
title_full The prepulse inhibition deficit appearance is largely independent on the circadian cycle, body weight, and the gender of vasopressin deficient Brattleboro rat
title_fullStr The prepulse inhibition deficit appearance is largely independent on the circadian cycle, body weight, and the gender of vasopressin deficient Brattleboro rat
title_full_unstemmed The prepulse inhibition deficit appearance is largely independent on the circadian cycle, body weight, and the gender of vasopressin deficient Brattleboro rat
title_sort prepulse inhibition deficit appearance is largely independent on the circadian cycle, body weight, and the gender of vasopressin deficient brattleboro rat
publisher Sciendo
publishDate 2016
url https://doaj.org/article/cb4277cd94f44a72a79a12dfd63baa48
work_keys_str_mv AT fodora theprepulseinhibitiondeficitappearanceislargelyindependentonthecircadiancyclebodyweightandthegenderofvasopressindeficientbrattlebororat
AT klauszb theprepulseinhibitiondeficitappearanceislargelyindependentonthecircadiancyclebodyweightandthegenderofvasopressindeficientbrattlebororat
AT tothb theprepulseinhibitiondeficitappearanceislargelyindependentonthecircadiancyclebodyweightandthegenderofvasopressindeficientbrattlebororat
AT zelenad theprepulseinhibitiondeficitappearanceislargelyindependentonthecircadiancyclebodyweightandthegenderofvasopressindeficientbrattlebororat
AT fodora prepulseinhibitiondeficitappearanceislargelyindependentonthecircadiancyclebodyweightandthegenderofvasopressindeficientbrattlebororat
AT klauszb prepulseinhibitiondeficitappearanceislargelyindependentonthecircadiancyclebodyweightandthegenderofvasopressindeficientbrattlebororat
AT tothb prepulseinhibitiondeficitappearanceislargelyindependentonthecircadiancyclebodyweightandthegenderofvasopressindeficientbrattlebororat
AT zelenad prepulseinhibitiondeficitappearanceislargelyindependentonthecircadiancyclebodyweightandthegenderofvasopressindeficientbrattlebororat
_version_ 1718387169494564864