The prepulse inhibition deficit appearance is largely independent on the circadian cycle, body weight, and the gender of vasopressin deficient Brattleboro rat
Objective. A disturbance of sensorimotor gating measured by prepulse inhibition of acoustic startle (PPI) is one of the best tests of the schizophrenia-like behavior. Vasopressin was implicated in the development of schizophrenia; therefore, the naturally occurring vasopressin-deficient Brattleboro...
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2016
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oai:doaj.org-article:cb4277cd94f44a72a79a12dfd63baa482021-12-02T15:29:49ZThe prepulse inhibition deficit appearance is largely independent on the circadian cycle, body weight, and the gender of vasopressin deficient Brattleboro rat1336-032910.1515/enr-2016-0004https://doaj.org/article/cb4277cd94f44a72a79a12dfd63baa482016-01-01T00:00:00Zhttps://doi.org/10.1515/enr-2016-0004https://doaj.org/toc/1336-0329Objective. A disturbance of sensorimotor gating measured by prepulse inhibition of acoustic startle (PPI) is one of the best tests of the schizophrenia-like behavior. Vasopressin was implicated in the development of schizophrenia; therefore, the naturally occurring vasopressin-deficient Brattleboro rat has been suggested to be a reliable non-pharmacological animal model. However, previous studies focusing on PPI deficit did not use proper control and despite clear gender differences in the development of the disorder, the effect of gender has been mostly neglected.Fodor AKlausz BToth BZelena DSciendoarticleschizophreniaketaminemalefemalelactationacoustic startle responseDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 50, Iss 1, Pp 16-23 (2016) |
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schizophrenia ketamine male female lactation acoustic startle response Diseases of the endocrine glands. Clinical endocrinology RC648-665 |
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schizophrenia ketamine male female lactation acoustic startle response Diseases of the endocrine glands. Clinical endocrinology RC648-665 Fodor A Klausz B Toth B Zelena D The prepulse inhibition deficit appearance is largely independent on the circadian cycle, body weight, and the gender of vasopressin deficient Brattleboro rat |
description |
Objective. A disturbance of sensorimotor gating measured by prepulse inhibition of acoustic startle (PPI) is one of the best tests of the schizophrenia-like behavior. Vasopressin was implicated in the development of schizophrenia; therefore, the naturally occurring vasopressin-deficient Brattleboro rat has been suggested to be a reliable non-pharmacological animal model. However, previous studies focusing on PPI deficit did not use proper control and despite clear gender differences in the development of the disorder, the effect of gender has been mostly neglected. |
format |
article |
author |
Fodor A Klausz B Toth B Zelena D |
author_facet |
Fodor A Klausz B Toth B Zelena D |
author_sort |
Fodor A |
title |
The prepulse inhibition deficit appearance is largely independent on the circadian cycle, body weight, and the gender of vasopressin deficient Brattleboro rat |
title_short |
The prepulse inhibition deficit appearance is largely independent on the circadian cycle, body weight, and the gender of vasopressin deficient Brattleboro rat |
title_full |
The prepulse inhibition deficit appearance is largely independent on the circadian cycle, body weight, and the gender of vasopressin deficient Brattleboro rat |
title_fullStr |
The prepulse inhibition deficit appearance is largely independent on the circadian cycle, body weight, and the gender of vasopressin deficient Brattleboro rat |
title_full_unstemmed |
The prepulse inhibition deficit appearance is largely independent on the circadian cycle, body weight, and the gender of vasopressin deficient Brattleboro rat |
title_sort |
prepulse inhibition deficit appearance is largely independent on the circadian cycle, body weight, and the gender of vasopressin deficient brattleboro rat |
publisher |
Sciendo |
publishDate |
2016 |
url |
https://doaj.org/article/cb4277cd94f44a72a79a12dfd63baa48 |
work_keys_str_mv |
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