A synthetic microbial biosensor for high-throughput screening of lactam biocatalysts
Efficient biosynthesis of lactams is still undesirable due to lacking of suitable enzyme. Here, the authors develop a sensitive transcription factor-based biosensor for high-throughput screening of marine metagenome and find a cyclase that can cyclize ω-amino fatty acids to lactam.
Guardado en:
Autores principales: | Soo-Jin Yeom, Moonjeong Kim, Kil Koang Kwon, Yaoyao Fu, Eugene Rha, Sung-Hyun Park, Hyewon Lee, Haseong Kim, Dae-Hee Lee, Dong-Myung Kim, Seung-Goo Lee |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/cb428eca6741429aa58b48b7daf262a2 |
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