Pathophysiological changes at single and multiple introduction of Ciprofloxacin solution under experimental conditions

The article presents the results of experimental biological modelling of single and subacute introduction of Ciprofloxacin to the rabbits. State of an organism of animals was estimated by biochemical, hematological, hemostatic and morphologic indices. Introduction of preparation samples was intraven...

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Autores principales:	A. G. Yushkov, M. M. Rasulov, P. A. Storozhenko, G. G. Yushkov, N. A. Shulgina, A. A. Gushchina
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2013
Materias:	ciprofloxacin toxicological research Science Q
Acceso en línea:	https://doaj.org/article/cb4326fa9608471bb5bb7d72daa94a31
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spelling	oai:doaj.org-article:cb4326fa9608471bb5bb7d72daa94a312021-11-23T06:14:29ZPathophysiological changes at single and multiple introduction of Ciprofloxacin solution under experimental conditions2541-94202587-9596https://doaj.org/article/cb4326fa9608471bb5bb7d72daa94a312013-09-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1666https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The article presents the results of experimental biological modelling of single and subacute introduction of Ciprofloxacin to the rabbits. State of an organism of animals was estimated by biochemical, hematological, hemostatic and morphologic indices. Introduction of preparation samples was intravenous, according to the Instruction of medical use. Main result of the experiments is determination of toxic effects that are typical for fluorinequinolone and developed on the background of multiple introduction of preparation in the doses higher than therapeutic.A. G. YushkovM. M. RasulovP. A. StorozhenkoG. G. YushkovN. A. ShulginaA. A. GushchinaScientific Сentre for Family Health and Human Reproduction Problemsarticleciprofloxacintoxicological researchScienceQRUActa Biomedica Scientifica, Vol 0, Iss 5, Pp 167-171 (2013)
institution	DOAJ
collection	DOAJ
language	RU
topic	ciprofloxacin toxicological research Science Q
spellingShingle	ciprofloxacin toxicological research Science Q A. G. Yushkov M. M. Rasulov P. A. Storozhenko G. G. Yushkov N. A. Shulgina A. A. Gushchina Pathophysiological changes at single and multiple introduction of Ciprofloxacin solution under experimental conditions
description	The article presents the results of experimental biological modelling of single and subacute introduction of Ciprofloxacin to the rabbits. State of an organism of animals was estimated by biochemical, hematological, hemostatic and morphologic indices. Introduction of preparation samples was intravenous, according to the Instruction of medical use. Main result of the experiments is determination of toxic effects that are typical for fluorinequinolone and developed on the background of multiple introduction of preparation in the doses higher than therapeutic.
format	article
author	A. G. Yushkov M. M. Rasulov P. A. Storozhenko G. G. Yushkov N. A. Shulgina A. A. Gushchina
author_facet	A. G. Yushkov M. M. Rasulov P. A. Storozhenko G. G. Yushkov N. A. Shulgina A. A. Gushchina
author_sort	A. G. Yushkov
title	Pathophysiological changes at single and multiple introduction of Ciprofloxacin solution under experimental conditions
title_short	Pathophysiological changes at single and multiple introduction of Ciprofloxacin solution under experimental conditions
title_full	Pathophysiological changes at single and multiple introduction of Ciprofloxacin solution under experimental conditions
title_fullStr	Pathophysiological changes at single and multiple introduction of Ciprofloxacin solution under experimental conditions
title_full_unstemmed	Pathophysiological changes at single and multiple introduction of Ciprofloxacin solution under experimental conditions
title_sort	pathophysiological changes at single and multiple introduction of ciprofloxacin solution under experimental conditions
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2013
url	https://doaj.org/article/cb4326fa9608471bb5bb7d72daa94a31
work_keys_str_mv	AT agyushkov pathophysiologicalchangesatsingleandmultipleintroductionofciprofloxacinsolutionunderexperimentalconditions AT mmrasulov pathophysiologicalchangesatsingleandmultipleintroductionofciprofloxacinsolutionunderexperimentalconditions AT pastorozhenko pathophysiologicalchangesatsingleandmultipleintroductionofciprofloxacinsolutionunderexperimentalconditions AT ggyushkov pathophysiologicalchangesatsingleandmultipleintroductionofciprofloxacinsolutionunderexperimentalconditions AT nashulgina pathophysiologicalchangesatsingleandmultipleintroductionofciprofloxacinsolutionunderexperimentalconditions AT aagushchina pathophysiologicalchangesatsingleandmultipleintroductionofciprofloxacinsolutionunderexperimentalconditions
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Pathophysiological changes at single and multiple introduction of Ciprofloxacin solution under experimental conditions

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