A review of quetiapine in combination with antidepressant therapy in patients with depression

Ella J Daly, Madhukar H TrivediMood Disorders Program, Department of Psychiatry, University of Texas Southwestern Medical School, Dallas, TX, USABackground: Atypical antipsychotics are increasingly used in the treatment of a broad spectrum of psychiatric disorders. There is evidence that in addition...

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Autores principales:	Ella J Daly, Madhukar H Trivedi
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2007
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/cb43fc24c1584018a5f301d00adae4f8
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spelling	oai:doaj.org-article:cb43fc24c1584018a5f301d00adae4f82021-12-02T01:58:21ZA review of quetiapine in combination with antidepressant therapy in patients with depression1176-63281178-2021https://doaj.org/article/cb43fc24c1584018a5f301d00adae4f82007-01-01T00:00:00Zhttp://www.dovepress.com/a-review-of-quetiapine-in-combination-with-antidepressant-therapy-in-p-a964https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Ella J Daly, Madhukar H TrivediMood Disorders Program, Department of Psychiatry, University of Texas Southwestern Medical School, Dallas, TX, USABackground: Atypical antipsychotics are increasingly used in the treatment of a broad spectrum of psychiatric disorders. There is evidence that in addition to treating the positive and negative symptoms of schizophrenia, as well as mania in bipolar disorder, these agents may have a potential role to play in the treatment of depressive disorders. In the following article we review the literature regarding the role of atypical antipsychotics, and specifically, quetiapine, in the treatment of major depressive disorder.Materials and methods: In March 2007 the authors performed a Medline search (English-language) using the keywords quetiapine and depression, revealing a total of 47 articles published. We also looked for cross-references in the published articles, obtained data-on-file from AstraZeneca Pharmaceutical L.P., and included abstracts presented at conferences and recent meetings.Results: From our review we found that there is increasing literature supporting the efficacy of add-on quetiapine in the treatment of major depressive disorder.Conclusion: There is a need, however, for further well-designed, adequately powered, randomized, controlled trials to confirm this finding, specifically in unipolar depression.Keywords: depression, adjunctive treatment, atypical antipsychotics, quetiapine Ella J DalyMadhukar H TrivediDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2007, Iss Issue 6, Pp 855-867 (2007)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Ella J Daly Madhukar H Trivedi A review of quetiapine in combination with antidepressant therapy in patients with depression
description	Ella J Daly, Madhukar H TrivediMood Disorders Program, Department of Psychiatry, University of Texas Southwestern Medical School, Dallas, TX, USABackground: Atypical antipsychotics are increasingly used in the treatment of a broad spectrum of psychiatric disorders. There is evidence that in addition to treating the positive and negative symptoms of schizophrenia, as well as mania in bipolar disorder, these agents may have a potential role to play in the treatment of depressive disorders. In the following article we review the literature regarding the role of atypical antipsychotics, and specifically, quetiapine, in the treatment of major depressive disorder.Materials and methods: In March 2007 the authors performed a Medline search (English-language) using the keywords quetiapine and depression, revealing a total of 47 articles published. We also looked for cross-references in the published articles, obtained data-on-file from AstraZeneca Pharmaceutical L.P., and included abstracts presented at conferences and recent meetings.Results: From our review we found that there is increasing literature supporting the efficacy of add-on quetiapine in the treatment of major depressive disorder.Conclusion: There is a need, however, for further well-designed, adequately powered, randomized, controlled trials to confirm this finding, specifically in unipolar depression.Keywords: depression, adjunctive treatment, atypical antipsychotics, quetiapine
format	article
author	Ella J Daly Madhukar H Trivedi
author_facet	Ella J Daly Madhukar H Trivedi
author_sort	Ella J Daly
title	A review of quetiapine in combination with antidepressant therapy in patients with depression
title_short	A review of quetiapine in combination with antidepressant therapy in patients with depression
title_full	A review of quetiapine in combination with antidepressant therapy in patients with depression
title_fullStr	A review of quetiapine in combination with antidepressant therapy in patients with depression
title_full_unstemmed	A review of quetiapine in combination with antidepressant therapy in patients with depression
title_sort	review of quetiapine in combination with antidepressant therapy in patients with depression
publisher	Dove Medical Press
publishDate	2007
url	https://doaj.org/article/cb43fc24c1584018a5f301d00adae4f8
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A review of quetiapine in combination with antidepressant therapy in patients with depression

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