Automated reporter quantification in vivo: high-throughput screening method for reporter-based assays in zebrafish.
Reporter-based assays underlie many high-throughput screening (HTS) platforms, but most are limited to in vitro applications. Here, we report a simple whole-organism HTS method for quantifying changes in reporter intensity in individual zebrafish over time termed, Automated Reporter Quantification i...
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Main Authors: | Steven L Walker, Junko Ariga, Jonathan R Mathias, Veena Coothankandaswamy, Xiayang Xie, Martin Distel, Reinhard W Köster, Michael J Parsons, Kapil N Bhalla, Meera T Saxena, Jeff S Mumm |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2012
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Subjects: | |
Online Access: | https://doaj.org/article/cb453aee935a411d96f8838e1cb39404 |
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