Coarse-grained simulation reveals key features of HIV-1 capsid self-assembly

Coarse-grained simulation reveals key features of HIV-1 capsid self-assembly

Significant morphological changes occur during the conversion of the immature HIV virion into a mature infectious form. Here the authors use coarse-grained molecular dynamics simulations to model HIV-1 capsid self-assembly and disassembly events that suggests several metastable capsid intermediates...

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Autores principales: John M. A. Grime, James F. Dama, Barbie K. Ganser-Pornillos, Cora L. Woodward, Grant J. Jensen, Mark Yeager, Gregory A. Voth
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Science
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Acceso en línea:https://doaj.org/article/cb54a296583545b2ab2085fab3f7c41c
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