Deep learning enables structured illumination microscopy with low light levels and enhanced speed
Super-resolution microscopy typically requires high laser powers which can induce photobleaching and degrade image quality. Here the authors augment structured illumination microscopy (SIM) with deep learning to reduce the number of raw images required and boost its performance under low light condi...
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Nature Portfolio
2020
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oai:doaj.org-article:cb59b1d9328d413d81e5520a618431fc2021-12-02T16:49:16ZDeep learning enables structured illumination microscopy with low light levels and enhanced speed10.1038/s41467-020-15784-x2041-1723https://doaj.org/article/cb59b1d9328d413d81e5520a618431fc2020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15784-xhttps://doaj.org/toc/2041-1723Super-resolution microscopy typically requires high laser powers which can induce photobleaching and degrade image quality. Here the authors augment structured illumination microscopy (SIM) with deep learning to reduce the number of raw images required and boost its performance under low light conditions.Luhong JinBei LiuFenqiang ZhaoStephen HahnBowei DongRuiyan SongTimothy C. ElstonYingke XuKlaus M. HahnNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-7 (2020) |
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Science Q Luhong Jin Bei Liu Fenqiang Zhao Stephen Hahn Bowei Dong Ruiyan Song Timothy C. Elston Yingke Xu Klaus M. Hahn Deep learning enables structured illumination microscopy with low light levels and enhanced speed |
description |
Super-resolution microscopy typically requires high laser powers which can induce photobleaching and degrade image quality. Here the authors augment structured illumination microscopy (SIM) with deep learning to reduce the number of raw images required and boost its performance under low light conditions. |
format |
article |
author |
Luhong Jin Bei Liu Fenqiang Zhao Stephen Hahn Bowei Dong Ruiyan Song Timothy C. Elston Yingke Xu Klaus M. Hahn |
author_facet |
Luhong Jin Bei Liu Fenqiang Zhao Stephen Hahn Bowei Dong Ruiyan Song Timothy C. Elston Yingke Xu Klaus M. Hahn |
author_sort |
Luhong Jin |
title |
Deep learning enables structured illumination microscopy with low light levels and enhanced speed |
title_short |
Deep learning enables structured illumination microscopy with low light levels and enhanced speed |
title_full |
Deep learning enables structured illumination microscopy with low light levels and enhanced speed |
title_fullStr |
Deep learning enables structured illumination microscopy with low light levels and enhanced speed |
title_full_unstemmed |
Deep learning enables structured illumination microscopy with low light levels and enhanced speed |
title_sort |
deep learning enables structured illumination microscopy with low light levels and enhanced speed |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/cb59b1d9328d413d81e5520a618431fc |
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