Deep learning enables structured illumination microscopy with low light levels and enhanced speed

Super-resolution microscopy typically requires high laser powers which can induce photobleaching and degrade image quality. Here the authors augment structured illumination microscopy (SIM) with deep learning to reduce the number of raw images required and boost its performance under low light condi...

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Autores principales: Luhong Jin, Bei Liu, Fenqiang Zhao, Stephen Hahn, Bowei Dong, Ruiyan Song, Timothy C. Elston, Yingke Xu, Klaus M. Hahn
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/cb59b1d9328d413d81e5520a618431fc
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spelling oai:doaj.org-article:cb59b1d9328d413d81e5520a618431fc2021-12-02T16:49:16ZDeep learning enables structured illumination microscopy with low light levels and enhanced speed10.1038/s41467-020-15784-x2041-1723https://doaj.org/article/cb59b1d9328d413d81e5520a618431fc2020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15784-xhttps://doaj.org/toc/2041-1723Super-resolution microscopy typically requires high laser powers which can induce photobleaching and degrade image quality. Here the authors augment structured illumination microscopy (SIM) with deep learning to reduce the number of raw images required and boost its performance under low light conditions.Luhong JinBei LiuFenqiang ZhaoStephen HahnBowei DongRuiyan SongTimothy C. ElstonYingke XuKlaus M. HahnNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Luhong Jin
Bei Liu
Fenqiang Zhao
Stephen Hahn
Bowei Dong
Ruiyan Song
Timothy C. Elston
Yingke Xu
Klaus M. Hahn
Deep learning enables structured illumination microscopy with low light levels and enhanced speed
description Super-resolution microscopy typically requires high laser powers which can induce photobleaching and degrade image quality. Here the authors augment structured illumination microscopy (SIM) with deep learning to reduce the number of raw images required and boost its performance under low light conditions.
format article
author Luhong Jin
Bei Liu
Fenqiang Zhao
Stephen Hahn
Bowei Dong
Ruiyan Song
Timothy C. Elston
Yingke Xu
Klaus M. Hahn
author_facet Luhong Jin
Bei Liu
Fenqiang Zhao
Stephen Hahn
Bowei Dong
Ruiyan Song
Timothy C. Elston
Yingke Xu
Klaus M. Hahn
author_sort Luhong Jin
title Deep learning enables structured illumination microscopy with low light levels and enhanced speed
title_short Deep learning enables structured illumination microscopy with low light levels and enhanced speed
title_full Deep learning enables structured illumination microscopy with low light levels and enhanced speed
title_fullStr Deep learning enables structured illumination microscopy with low light levels and enhanced speed
title_full_unstemmed Deep learning enables structured illumination microscopy with low light levels and enhanced speed
title_sort deep learning enables structured illumination microscopy with low light levels and enhanced speed
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/cb59b1d9328d413d81e5520a618431fc
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