Spontaneous bacterial peritonitis: update on diagnosis and treatment

Spontaneous bacterial peritonitis (SBP) is a common complication in patients with liver cirrhosis, with an increased risk of mortality. For this reason, a diagnostic paracentesis should be performed in all patients with ascites and clinical features with high diagnostic suspicion. Although literatur...

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Autores principales:	Popoiag Roxana-Emanuela, Fierbințeanu-Braticevici Carmen
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2021
Materias:	spontaneous bacterial peritonitis cirrhosis paracentesis multidrug-resistant organisms Internal medicine RC31-1245
Acceso en línea:	https://doaj.org/article/cb614bfc5c7c43c0a9132ae311eefab3
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id	oai:doaj.org-article:cb614bfc5c7c43c0a9132ae311eefab3
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spelling	oai:doaj.org-article:cb614bfc5c7c43c0a9132ae311eefab32021-12-05T14:11:10ZSpontaneous bacterial peritonitis: update on diagnosis and treatment2501-062X10.2478/rjim-2021-0024https://doaj.org/article/cb614bfc5c7c43c0a9132ae311eefab32021-12-01T00:00:00Zhttps://doi.org/10.2478/rjim-2021-0024https://doaj.org/toc/2501-062XSpontaneous bacterial peritonitis (SBP) is a common complication in patients with liver cirrhosis, with an increased risk of mortality. For this reason, a diagnostic paracentesis should be performed in all patients with ascites and clinical features with high diagnostic suspicion. Although literature data abound in identifying new diagnostic markers in serum or ascites, they have not yet been validated. The final diagnosis requires the analysis of ascites and the presence of > 250 mm3 neutrophil polymorphonuclear (PMN) in ascites. If previous data showed that the most common microorganisms identified were represented by gram-negative bacteria, we are currently facing an increase in gram-positive bacteria and multidrug-resistant bacteria. Although prompt and effective treatment is required to prevent outcomes, this becomes challenging as first-line therapies may become ineffective leading to worsening prognosis and increased in-hospital mortality. In this paper we will make a brief review of existing data on the diagnosis and treatment of SBP.Popoiag Roxana-EmanuelaFierbințeanu-Braticevici CarmenSciendoarticlespontaneous bacterial peritonitiscirrhosisparacentesismultidrug-resistant organismsInternal medicineRC31-1245ENRomanian Journal of Internal Medicine, Vol 59, Iss 4, Pp 345-350 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	spontaneous bacterial peritonitis cirrhosis paracentesis multidrug-resistant organisms Internal medicine RC31-1245
spellingShingle	spontaneous bacterial peritonitis cirrhosis paracentesis multidrug-resistant organisms Internal medicine RC31-1245 Popoiag Roxana-Emanuela Fierbințeanu-Braticevici Carmen Spontaneous bacterial peritonitis: update on diagnosis and treatment
description	Spontaneous bacterial peritonitis (SBP) is a common complication in patients with liver cirrhosis, with an increased risk of mortality. For this reason, a diagnostic paracentesis should be performed in all patients with ascites and clinical features with high diagnostic suspicion. Although literature data abound in identifying new diagnostic markers in serum or ascites, they have not yet been validated. The final diagnosis requires the analysis of ascites and the presence of > 250 mm3 neutrophil polymorphonuclear (PMN) in ascites. If previous data showed that the most common microorganisms identified were represented by gram-negative bacteria, we are currently facing an increase in gram-positive bacteria and multidrug-resistant bacteria. Although prompt and effective treatment is required to prevent outcomes, this becomes challenging as first-line therapies may become ineffective leading to worsening prognosis and increased in-hospital mortality. In this paper we will make a brief review of existing data on the diagnosis and treatment of SBP.
format	article
author	Popoiag Roxana-Emanuela Fierbințeanu-Braticevici Carmen
author_facet	Popoiag Roxana-Emanuela Fierbințeanu-Braticevici Carmen
author_sort	Popoiag Roxana-Emanuela
title	Spontaneous bacterial peritonitis: update on diagnosis and treatment
title_short	Spontaneous bacterial peritonitis: update on diagnosis and treatment
title_full	Spontaneous bacterial peritonitis: update on diagnosis and treatment
title_fullStr	Spontaneous bacterial peritonitis: update on diagnosis and treatment
title_full_unstemmed	Spontaneous bacterial peritonitis: update on diagnosis and treatment
title_sort	spontaneous bacterial peritonitis: update on diagnosis and treatment
publisher	Sciendo
publishDate	2021
url	https://doaj.org/article/cb614bfc5c7c43c0a9132ae311eefab3
work_keys_str_mv	AT popoiagroxanaemanuela spontaneousbacterialperitonitisupdateondiagnosisandtreatment AT fierbinteanubraticevicicarmen spontaneousbacterialperitonitisupdateondiagnosisandtreatment
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Spontaneous bacterial peritonitis: update on diagnosis and treatment

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