Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass
X-chromosome inactivation is reversed in the mouse inner cell mass (ICM) through a mechanism that is not fully understood. Here, the authors investigate this process and characterize the contributions of the epigenetic landscape and transcription factors in X-linked gene reactivation dynamics.
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Nature Portfolio
2017
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oai:doaj.org-article:cb63d7d22fc842af90dbf976ae402b392021-12-02T17:06:27ZContribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass10.1038/s41467-017-01415-52041-1723https://doaj.org/article/cb63d7d22fc842af90dbf976ae402b392017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01415-5https://doaj.org/toc/2041-1723X-chromosome inactivation is reversed in the mouse inner cell mass (ICM) through a mechanism that is not fully understood. Here, the authors investigate this process and characterize the contributions of the epigenetic landscape and transcription factors in X-linked gene reactivation dynamics.Maud BorenszteinIkuhiro OkamotoLaurène SyxGuillaume GuilbaudChristel PicardKatia AncelinRafael GalupaPatricia DiabangouayaNicolas ServantEmmanuel BarillotAzim SuraniMitinori SaitouChong-Jian ChenKonstantinos AnastassiadisEdith HeardNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017) |
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Science Q |
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Science Q Maud Borensztein Ikuhiro Okamoto Laurène Syx Guillaume Guilbaud Christel Picard Katia Ancelin Rafael Galupa Patricia Diabangouaya Nicolas Servant Emmanuel Barillot Azim Surani Mitinori Saitou Chong-Jian Chen Konstantinos Anastassiadis Edith Heard Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass |
description |
X-chromosome inactivation is reversed in the mouse inner cell mass (ICM) through a mechanism that is not fully understood. Here, the authors investigate this process and characterize the contributions of the epigenetic landscape and transcription factors in X-linked gene reactivation dynamics. |
format |
article |
author |
Maud Borensztein Ikuhiro Okamoto Laurène Syx Guillaume Guilbaud Christel Picard Katia Ancelin Rafael Galupa Patricia Diabangouaya Nicolas Servant Emmanuel Barillot Azim Surani Mitinori Saitou Chong-Jian Chen Konstantinos Anastassiadis Edith Heard |
author_facet |
Maud Borensztein Ikuhiro Okamoto Laurène Syx Guillaume Guilbaud Christel Picard Katia Ancelin Rafael Galupa Patricia Diabangouaya Nicolas Servant Emmanuel Barillot Azim Surani Mitinori Saitou Chong-Jian Chen Konstantinos Anastassiadis Edith Heard |
author_sort |
Maud Borensztein |
title |
Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass |
title_short |
Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass |
title_full |
Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass |
title_fullStr |
Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass |
title_full_unstemmed |
Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass |
title_sort |
contribution of epigenetic landscapes and transcription factors to x-chromosome reactivation in the inner cell mass |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/cb63d7d22fc842af90dbf976ae402b39 |
work_keys_str_mv |
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