Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass

X-chromosome inactivation is reversed in the mouse inner cell mass (ICM) through a mechanism that is not fully understood. Here, the authors investigate this process and characterize the contributions of the epigenetic landscape and transcription factors in X-linked gene reactivation dynamics.

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Autores principales: Maud Borensztein, Ikuhiro Okamoto, Laurène Syx, Guillaume Guilbaud, Christel Picard, Katia Ancelin, Rafael Galupa, Patricia Diabangouaya, Nicolas Servant, Emmanuel Barillot, Azim Surani, Mitinori Saitou, Chong-Jian Chen, Konstantinos Anastassiadis, Edith Heard
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/cb63d7d22fc842af90dbf976ae402b39
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spelling oai:doaj.org-article:cb63d7d22fc842af90dbf976ae402b392021-12-02T17:06:27ZContribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass10.1038/s41467-017-01415-52041-1723https://doaj.org/article/cb63d7d22fc842af90dbf976ae402b392017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01415-5https://doaj.org/toc/2041-1723X-chromosome inactivation is reversed in the mouse inner cell mass (ICM) through a mechanism that is not fully understood. Here, the authors investigate this process and characterize the contributions of the epigenetic landscape and transcription factors in X-linked gene reactivation dynamics.Maud BorenszteinIkuhiro OkamotoLaurène SyxGuillaume GuilbaudChristel PicardKatia AncelinRafael GalupaPatricia DiabangouayaNicolas ServantEmmanuel BarillotAzim SuraniMitinori SaitouChong-Jian ChenKonstantinos AnastassiadisEdith HeardNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Maud Borensztein
Ikuhiro Okamoto
Laurène Syx
Guillaume Guilbaud
Christel Picard
Katia Ancelin
Rafael Galupa
Patricia Diabangouaya
Nicolas Servant
Emmanuel Barillot
Azim Surani
Mitinori Saitou
Chong-Jian Chen
Konstantinos Anastassiadis
Edith Heard
Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass
description X-chromosome inactivation is reversed in the mouse inner cell mass (ICM) through a mechanism that is not fully understood. Here, the authors investigate this process and characterize the contributions of the epigenetic landscape and transcription factors in X-linked gene reactivation dynamics.
format article
author Maud Borensztein
Ikuhiro Okamoto
Laurène Syx
Guillaume Guilbaud
Christel Picard
Katia Ancelin
Rafael Galupa
Patricia Diabangouaya
Nicolas Servant
Emmanuel Barillot
Azim Surani
Mitinori Saitou
Chong-Jian Chen
Konstantinos Anastassiadis
Edith Heard
author_facet Maud Borensztein
Ikuhiro Okamoto
Laurène Syx
Guillaume Guilbaud
Christel Picard
Katia Ancelin
Rafael Galupa
Patricia Diabangouaya
Nicolas Servant
Emmanuel Barillot
Azim Surani
Mitinori Saitou
Chong-Jian Chen
Konstantinos Anastassiadis
Edith Heard
author_sort Maud Borensztein
title Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass
title_short Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass
title_full Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass
title_fullStr Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass
title_full_unstemmed Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass
title_sort contribution of epigenetic landscapes and transcription factors to x-chromosome reactivation in the inner cell mass
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/cb63d7d22fc842af90dbf976ae402b39
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