Condition of Lipids and Lipoproteins in normal subjects and in acute and stable phases of myocardial infarction

Objective: Measurement of lipids and lipoproteins is important in screening, prognosis and treatment of myocardial infarction (MI). The purpose of this study was to determine the level of lipids and lipoproteins in normal subjects, acute phase and also two weeks after incidence of MI in stable phase...

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Autores principales: S Mahjoub, M Taghi Khani, H Amir Rasouli, F Noohi
Formato: article
Lenguaje:EN
FA
Publicado: Babol University of Medical Sciences 2001
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spelling oai:doaj.org-article:cb6ada033ea24643ab5558d8d94693ab2021-11-10T09:21:06ZCondition of Lipids and Lipoproteins in normal subjects and in acute and stable phases of myocardial infarction1561-41072251-7170https://doaj.org/article/cb6ada033ea24643ab5558d8d94693ab2001-07-01T00:00:00Zhttp://jbums.org/article-1-2862-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Objective: Measurement of lipids and lipoproteins is important in screening, prognosis and treatment of myocardial infarction (MI). The purpose of this study was to determine the level of lipids and lipoproteins in normal subjects, acute phase and also two weeks after incidence of MI in stable phase. Methods: This study was done on 130 normal subjects and 130 patients with MI. Triglyceride (TG), total cholesterol, HDL-C, VLDL-C and LDL-C were measured in normal subjects and in acute and stable phases. Systolic and diastolic blood pressure and frequency of risk factors such as smoking, familial hyperlipidemia, diabetes mellitus and familial history of MI were surveyed. T-test and Chi-square test were done to analyze the results and P<0.05 was statistically considered significant. Findings: Mean of total cholesterol, triglyceride, LDL-C, VLDL-C in stable phase in comparison to acute phase decreased but there was not a significant difference. Whereas, they were higher in acute and stable phases in comparison to control group (P<0.0001). Also, the mean of HDL-C in stable phase was higher than acute phase with no significant difference and it was lower in stable and acute phases in comparison to control group (P<0.001). The frequency of risk factors except smoking in females is more than in males (P<0.05). Conclusion: The results indicate that there is a decline in the plasma level of lipids and lipoproteins in stable phase. So, we suggest nutritional regimen and medication for patients with MI during and after hospitalization. Also, the role of sex should be considered in emergence of risk factors in stages of screening, prognosis and treatment.S MahjoubM Taghi KhaniH Amir RasouliF NoohiBabol University of Medical Sciencesarticlemyocardial infarctionacute phasestable phaselipidlipoproteinrisk factorMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 3, Iss 3, Pp 30-36 (2001)
institution DOAJ
collection DOAJ
language EN
FA
topic myocardial infarction
acute phase
stable phase
lipid
lipoprotein
risk factor
Medicine
R
Medicine (General)
R5-920
spellingShingle myocardial infarction
acute phase
stable phase
lipid
lipoprotein
risk factor
Medicine
R
Medicine (General)
R5-920
S Mahjoub
M Taghi Khani
H Amir Rasouli
F Noohi
Condition of Lipids and Lipoproteins in normal subjects and in acute and stable phases of myocardial infarction
description Objective: Measurement of lipids and lipoproteins is important in screening, prognosis and treatment of myocardial infarction (MI). The purpose of this study was to determine the level of lipids and lipoproteins in normal subjects, acute phase and also two weeks after incidence of MI in stable phase. Methods: This study was done on 130 normal subjects and 130 patients with MI. Triglyceride (TG), total cholesterol, HDL-C, VLDL-C and LDL-C were measured in normal subjects and in acute and stable phases. Systolic and diastolic blood pressure and frequency of risk factors such as smoking, familial hyperlipidemia, diabetes mellitus and familial history of MI were surveyed. T-test and Chi-square test were done to analyze the results and P<0.05 was statistically considered significant. Findings: Mean of total cholesterol, triglyceride, LDL-C, VLDL-C in stable phase in comparison to acute phase decreased but there was not a significant difference. Whereas, they were higher in acute and stable phases in comparison to control group (P<0.0001). Also, the mean of HDL-C in stable phase was higher than acute phase with no significant difference and it was lower in stable and acute phases in comparison to control group (P<0.001). The frequency of risk factors except smoking in females is more than in males (P<0.05). Conclusion: The results indicate that there is a decline in the plasma level of lipids and lipoproteins in stable phase. So, we suggest nutritional regimen and medication for patients with MI during and after hospitalization. Also, the role of sex should be considered in emergence of risk factors in stages of screening, prognosis and treatment.
format article
author S Mahjoub
M Taghi Khani
H Amir Rasouli
F Noohi
author_facet S Mahjoub
M Taghi Khani
H Amir Rasouli
F Noohi
author_sort S Mahjoub
title Condition of Lipids and Lipoproteins in normal subjects and in acute and stable phases of myocardial infarction
title_short Condition of Lipids and Lipoproteins in normal subjects and in acute and stable phases of myocardial infarction
title_full Condition of Lipids and Lipoproteins in normal subjects and in acute and stable phases of myocardial infarction
title_fullStr Condition of Lipids and Lipoproteins in normal subjects and in acute and stable phases of myocardial infarction
title_full_unstemmed Condition of Lipids and Lipoproteins in normal subjects and in acute and stable phases of myocardial infarction
title_sort condition of lipids and lipoproteins in normal subjects and in acute and stable phases of myocardial infarction
publisher Babol University of Medical Sciences
publishDate 2001
url https://doaj.org/article/cb6ada033ea24643ab5558d8d94693ab
work_keys_str_mv AT smahjoub conditionoflipidsandlipoproteinsinnormalsubjectsandinacuteandstablephasesofmyocardialinfarction
AT mtaghikhani conditionoflipidsandlipoproteinsinnormalsubjectsandinacuteandstablephasesofmyocardialinfarction
AT hamirrasouli conditionoflipidsandlipoproteinsinnormalsubjectsandinacuteandstablephasesofmyocardialinfarction
AT fnoohi conditionoflipidsandlipoproteinsinnormalsubjectsandinacuteandstablephasesofmyocardialinfarction
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