Exploiting endogenous fibrocartilage stem cells to regenerate cartilage and repair joint injury

A potentially superior tissue regenerative strategy to stem cell transplantation is modulation of endogenous stem cells. Here the authors show fibrocartilage stem cells exist in the temporomandibular joint that contribute to cartilage regeneration and can be manipulated to enhance regeneration throu...

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Autores principales:	Mildred C. Embree, Mo Chen, Serhiy Pylawka, Danielle Kong, George M. Iwaoka, Ivo Kalajzic, Hai Yao, Chancheng Shi, Dongming Sun, Tzong-Jen Sheu, David A. Koslovsky, Alia Koch, Jeremy J. Mao
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/cb7252425b434505a45e5bfca648c7a8
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spelling	oai:doaj.org-article:cb7252425b434505a45e5bfca648c7a82021-12-02T17:32:05ZExploiting endogenous fibrocartilage stem cells to regenerate cartilage and repair joint injury10.1038/ncomms130732041-1723https://doaj.org/article/cb7252425b434505a45e5bfca648c7a82016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13073https://doaj.org/toc/2041-1723A potentially superior tissue regenerative strategy to stem cell transplantation is modulation of endogenous stem cells. Here the authors show fibrocartilage stem cells exist in the temporomandibular joint that contribute to cartilage regeneration and can be manipulated to enhance regeneration through canonical Wnt signalling.Mildred C. EmbreeMo ChenSerhiy PylawkaDanielle KongGeorge M. IwaokaIvo KalajzicHai YaoChancheng ShiDongming SunTzong-Jen SheuDavid A. KoslovskyAlia KochJeremy J. MaoNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mildred C. Embree Mo Chen Serhiy Pylawka Danielle Kong George M. Iwaoka Ivo Kalajzic Hai Yao Chancheng Shi Dongming Sun Tzong-Jen Sheu David A. Koslovsky Alia Koch Jeremy J. Mao Exploiting endogenous fibrocartilage stem cells to regenerate cartilage and repair joint injury
description	A potentially superior tissue regenerative strategy to stem cell transplantation is modulation of endogenous stem cells. Here the authors show fibrocartilage stem cells exist in the temporomandibular joint that contribute to cartilage regeneration and can be manipulated to enhance regeneration through canonical Wnt signalling.
format	article
author	Mildred C. Embree Mo Chen Serhiy Pylawka Danielle Kong George M. Iwaoka Ivo Kalajzic Hai Yao Chancheng Shi Dongming Sun Tzong-Jen Sheu David A. Koslovsky Alia Koch Jeremy J. Mao
author_facet	Mildred C. Embree Mo Chen Serhiy Pylawka Danielle Kong George M. Iwaoka Ivo Kalajzic Hai Yao Chancheng Shi Dongming Sun Tzong-Jen Sheu David A. Koslovsky Alia Koch Jeremy J. Mao
author_sort	Mildred C. Embree
title	Exploiting endogenous fibrocartilage stem cells to regenerate cartilage and repair joint injury
title_short	Exploiting endogenous fibrocartilage stem cells to regenerate cartilage and repair joint injury
title_full	Exploiting endogenous fibrocartilage stem cells to regenerate cartilage and repair joint injury
title_fullStr	Exploiting endogenous fibrocartilage stem cells to regenerate cartilage and repair joint injury
title_full_unstemmed	Exploiting endogenous fibrocartilage stem cells to regenerate cartilage and repair joint injury
title_sort	exploiting endogenous fibrocartilage stem cells to regenerate cartilage and repair joint injury
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/cb7252425b434505a45e5bfca648c7a8
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Exploiting endogenous fibrocartilage stem cells to regenerate cartilage and repair joint injury

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